Consensus terms for the PLCXc domain 

GM25027_1        HDMTLPLSHYFIYTGHN---------------------------------SYLTGNQLSS
CONSENSUS/80%    ...p.PLschhIsuoHN.................................oahhspphtu
CONSENSUS/65%    pDhspPLucYaIsoSHN.................................TYLhscQltu
CONSENSUS/50%    pDMspPLSHYaIsSSHN.................................TYLsG+QlsG


GM25027_1        DCSDVPIINALKRGVRVIELDIWPNASK------DNIDVLHGRTLTTPVELIRCLRSIKD
CONSENSUS/80%    .sp...ahp.LptGsRhl-lchhss.st      ...hlhHu..hh..l.hppslcsIpp
CONSENSUS/65%    .sospsYhpsLppGsRslElDhasusss      .psllhHGhshhptlthpcVlcsI+c
CONSENSUS/50%    cSSsEuYIpsLcpGCRClELDsWDGsDG      .cPllaHGaThTopIpLp-Vl-sIKc


GM25027_1        HAFVASEYP--VVITLEDHL--TPDLQAKVAEMVTETFGDLLFTPNSESVKE------FP
CONSENSUS/80%    hhhhss.hs..lllohc.th. s.tppthhsphhpphhsc.hh..s..st........hP
CONSENSUS/65%    aAFhsSsaP..lIlolcpah. s.ppQthhsphhcplhu-hLhspshpsspp......LP
CONSENSUS/50%    aAFssSsYP..VILSLEsHC. us-QQcpMAphh+ElFGDhLascPscuscp......LP


GM25027_1        SPESLKKRIIISTK
CONSENSUS/80%    s.tph+t+Illh.+
CONSENSUS/65%    oPppL+pKIllps+
CONSENSUS/50%    SPcpL+cKILLKsK

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T