Consensus terms for the PTB domain

3891508/1-131    SATCSFSVKYLGCVEVFESR--------GMQVCEEALKVLR-------------------
CONSENSUS/80%    ..s.thtshalGth.h.t.p. ......s.thhttshpph....................
CONSENSUS/65%    .tshpaplpYlGslplsptp. ......u.phhppslpplp...................
CONSENSUS/50%    ssuspFpVpYLGslcVscsc. ......GssslscAlcclpt..................


3891508/1-131    ------QSRRRPVRGLLHVSGDGLRVVDDETK-----------------------GLIVD
CONSENSUS/80%    ......t......th.h.ls.ttlplht.ptt...      ...............hhhp
CONSENSUS/65%    ......stttphpphhlplohpslplhstpsp...      ..............thlhp
CONSENSUS/50%    ....hsussppspslplplSscul+Llsscsc...      ..............plltc


3891508/1-131    QTIEKVSFCAPDR-----------------------------NHERGFSYICRDGTTR--
CONSENSUS/80%    h.h.plphhs.s...............................p.phhuhlhpp.st...
CONSENSUS/65%    hslppIoahuts..............................ppschFuals+ctss...
CONSENSUS/50%    aslppISFsuss..............................scscsFuals+csssp..


3891508/1-131    ------------------RWMCHGFLACKDS---GERLSHAVGCAFAVCLERKQRRTRA
CONSENSUS/80%    ...................h.hash.stt.t......h..shhthh.hhht...ttp..
CONSENSUS/65%    ..................phtCHlFtsppst.....tlstsltpsFphthptthpppp.
CONSENSUS/50%    ..................chpCHVFpCscss....pplspultpAFpssappppspspt

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T