Consensus terms for the PX domain

Q13596/1-128     DQFDL-TVGITDP---EKIGDGMNAYVAYKVTTQTSLPL-----------FRSKQFAVKR
CONSENSUS/80%    ..h...h..ht..........t...hhhhtlpht.......................h.+
CONSENSUS/65%    tthht.hthhp..........tpphhhhhplpppss..................thplhR
CONSENSUS/50%    ssltp.hsllssp....t.tsspptaallplpspss.................pppplpR


Q13596/1-128     RFSDFLGLYEKLSEKHSQN-----------------------------GFIVPPPPEKSL
CONSENSUS/80%    pap-F..hpp.L.t.h...............  ..  ............hhlP.hP.t..
CONSENSUS/65%    +as-FhtLcppLtpphs..............  ..  ...........thhlP.hPtcth
CONSENSUS/50%    RYS-FppL+spLpccas..............  ..  ...........pptlPslPsKph


Q13596/1-128     IG-----------------------------------------------------MTKVK
CONSENSUS/80%    ............................................................
CONSENSUS/65%    h...........................................................
CONSENSUS/50%    hst.........................................................


Q13596/1-128     VGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQ--------DPDVREFLEKE
CONSENSUS/80%    ........tphhppRt..Lptalptlht...h.t........s..hhpFht.t
CONSENSUS/65%    .......ppphhccRcttLppalpplhpts.hhp........schlhpFlpsp
CONSENSUS/50%    ......hscchl-cR+psLppYLpplsppPhlss........schltcFLpss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T