Consensus terms for the RA domain

E1357084/1-99    NEHTLRIYPGTIS---EGTIYCPIPARKNSTAAEVIDSLINRLHLDK---------TKCY
CONSENSUS/80%    t...l+lh.t........t..t.l.h..p.sstpllt.hhtchth.t..........tpa
CONSENSUS/65%    ppthl+lhhps.......pshpsltlsppsospcVlpthhp+htlss.........sppa
CONSENSUS/50%    cspslRVasss......sssh+slplsscsTsp-VlppllcKaplss........ssccY


E1357084/1-99    VLAEVKE------------FGGEEWILNPTDCPVQRMMLWPRMALENRLSGEDYRFLLRE
CONSENSUS/80%    .Lh.hh.....   .......th.hhl..tp.sh.h...h..............thhhpp
CONSENSUS/65%    sLhphh.....   ......tshcphl.ssppPl.hhtth.p............pahlcc
CONSENSUS/50%    sLlcpt.....   ......sspE+pLsss-pPlplhpshspp.......ttthpFlL++


E1357084/1-99    KNL
CONSENSUS/80%    pt.
CONSENSUS/65%    pss
CONSENSUS/50%    +ss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T