Consensus terms for the RAN domain 

P28746           VGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGL
CONSENSUS/80%    VGDGGTGKTTFVKRHLTGEFEKKY.sTlGVEVHPLsFaTNpG.I+F.sWDTAGQEKFGGL
CONSENSUS/65%    VGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGpIRFNVWDTAGQEKFGGL
CONSENSUS/50%    VGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGpIRFNVWDTAGQEKFGGL


P28746           RDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKS
CONSENSUS/80%    RDGYYIpuQCAIIMFDVTuRlTYKNVPsWHRDLsRVCENIPIVLCGNKVDlKsRpVKAKp
CONSENSUS/65%    RDGYYIQGQCAIIMFDVTARVTYKNVPNWHRDLsRVCENIPIVLCGNKVDVKDRKVKAKo
CONSENSUS/50%    RDGYYIQGQCAIIMFDVTARVTYKNVPNWHRDLsRVCENIPIVLCGNKVDVKDRKVKAKo


P28746           IVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAA
CONSENSUS/80%    lsFHRKKNLQYY-ISAKSNYNFEKPFLaLARKLhGD.NLcFVt.PALAPPEV.hD.Ah.s
CONSENSUS/65%    ITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLlGDPNLEFVAMPALAPPEVpMDPAhtA
CONSENSUS/50%    ITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLlGDPNLEFVAMPALAPPEVpMDPAhtA


P28746           QYEHDLEVAQTTALPD-EDDDL-
CONSENSUS/80%    p.EtDLtsAtttsLPD.-DDsh.
CONSENSUS/65%    cYE+DL-sAAsssLPD.DDDDL.
CONSENSUS/50%    cYE+DL-sAAsssLPD.DDDDL.

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T