Consensus terms for the RPOL4c domain 

O48890/16-138    DEFLKA--KCLMNC---EVSLILE--HKFEQLQQISEDP-----MNQVSQVFEKSLQYVK
CONSENSUS/80%    .ph.ss..pshh.t....h..hhp...+tppp-..otc.......t.hsplhhcohpYhs
CONSENSUS/65%    .-htss..psLh.s...-hphlh-..h+pppcE..Sscs......pplsplhhcThpYls
CONSENSUS/50%    hEFccA..ssLhsu...ElpLLL-..p+cpp+E..Su-s.....ppslsslhYcTLcYls


O48890/16-138    RFS-RYKNPDAVRQVREILSR-HQLTEFELCVLGNLCPETVEEAVAMVPSLKTKGRAH-D
CONSENSUS/80%    phs.phps.-hltphhphhtp.h+LpchEhhplhNhpP.os.Ehphhl.p.cp+...h.p
CONSENSUS/65%    chs.Raps.Eslpphhshhps.pKLpKhEhhpLhNLpPpTs.Ehphhl.ph-pR...l.s
CONSENSUS/50%    +ousRaQopEoVpchtstLKs.+KLsKAElLQLlNLpPpTAlElpslIEsLE-R...l.-


O48890/16-138    DEAIEKMLNDLSLVKRFE
CONSENSUS/80%    --plptllpsl.shh.ht
CONSENSUS/65%    -EplcplLcslsshhshp
CONSENSUS/50%    -EpIEpLLc-loolLPsp

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T