Consensus terms for the RTC4 domain 

4952.Q6CI81_from_293_to_428ILPLL-----------------------KAGGGDNHVFYKDITDYFSSPGARRAANTTQL
CONSENSUS/80%    ll............................tst...shahp.hpp..ptuptt.hthp..
CONSENSUS/65%    Il............................ssp..sShYhshhcphhpsuppcshphpt.
CONSENSUS/50%    IL............................sGcp.sSaY+shscsth+sGp++shsssph


4952.Q6CI81_from_293_to_428MYLGGRRYTTGYYSELFAHELNKHMTNSGLAQDFEHHVRSNPELHSMIIRPGLLFHFQTA
CONSENSUS/80%    .....pth.sGYYG.ct..hh.p.lhp.....pat..ltp....sthhthhs...ta.p.
CONSENSUS/65%    ...thpphpsGYYG.+ttthhsphlhs.....capppLpphs.pschlphhuss.sFsp.
CONSENSUS/50%    pthshcphosGYYGhRGppllucpIls.....+FsccL++pAtps+llshhGss.sFspt


4952.Q6CI81_from_293_to_428ICIPETVIRLIMDDQ------KVS----YEE----------------------------A
CONSENSUS/80%    VLssElhh.hhh--h......ths.....pp............................A
CONSENSUS/65%    VLsPElhlpllh-Dh......pls.....cp............................A
CONSENSUS/50%    VLVPElllpLlpEDM......sls....s--............................A


4952.Q6CI81_from_293_to_428DQIRLRSAEFGVVVAER
CONSENSUS/80%    .plh.po.phG.hlt.t
CONSENSUS/65%    hplhp-oschGthls-p
CONSENSUS/50%    csIhcESs-aGplls-s

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T