Consensus terms for the RasGEFN domain 

MMCDC25H_1/1-1   CKVLQIRYASVERLLERLTDLRF--------LSIDFLNTFLHSYRVFTNAMVVLDKLINI
CONSENSUS/80%    pt...l+.ushptLltplhtt...........s..a.tshLhsacshhssttlhthLh.h
CONSENSUS/65%    ssthhl+uuoh-tLlc+Lspphp........hD.paspsFLhTaRsFhostpllphLhpc
CONSENSUS/50%    sssspIKuGolE+Ll-HLocspp........sDssFlssFLtTYRoFhoos-LlstLlpR


MMCDC25H_1/1-1   YRKPMSAIPARSLEL-------XXKEVFRRMSLAN-----TGFSSDQRNIDKEFVIRRAA
CONSENSUS/80%    a.h........................................................h
CONSENSUS/65%    Yphh.s..............................................t..t...h
CONSENSUS/50%    Ypthssp.....................tp...................h.pphhsthpl


MMCDC25H_1/1-1   TNRVLNVLRHWVTKHTQ--DFDTDDTLKYRVIC--FLEEVMHDP-DLLTQERKAAANIIR
CONSENSUS/80%    p.thhplhhhhhpph....sa.tp.....hl.p..hhthht......h.t..tth.phht
CONSENSUS/65%    pt+lhpllphWlppahp..sFpps..hhhhlpp..hhphhptp....h.phhppltplhp
CONSENSUS/50%    ps+VlpllppWlcpaap..DFcscsphttpLcp..Ftchlcsc....hsptpssltsllp


MMCDC25H_1/1-1   TLT
CONSENSUS/80%    th.
CONSENSUS/65%    php
CONSENSUS/50%    pls

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T