Consensus terms for the SAR domain 

sar1_yeast       FGWFRDVLASLGLWNKHGKLLFLGLDNAGKTTLLHMLKNDRLATLQPTWHPTSEELAIGN
CONSENSUS/80%    hsWFhshLA.LGLhpKcuKhLFLGLDNAGKTTLLHMLKs-RLs.hQPT.HPTSEELuIGp
CONSENSUS/65%    FsWFYDlLASLGLWNKHAKlLFLGLDNAGKTTLLHMLKNDRLAshQPThHPTSEELAIGN
CONSENSUS/50%    FsWFYDlLASLGLWNKHAKlLFLGLDNAGKTTLLHMLKNDRLAshQPThHPTSEELAIGN


sar1_yeast       IKFTTFDLGGHIQARRLWKDYFPEVNGIVFLVDAADPE--RFDEARVELDALFNIAELKD
CONSENSUS/80%    l+FpsFDLGGH..ARRlW+DYascVsulVaLVDshD.E  RhsEu+hELDALhs.ttLtp
CONSENSUS/65%    IKFTTFDLGGHQQARRLWKDYFPEVNGIVYLVDAsDhE  RFuESKsELDALLuhEELAc
CONSENSUS/50%    IKFTTFDLGGHQQARRLWKDYFPEVNGIVYLVDAsDhE  RFuESKsELDALLuhEELAc


sar1_yeast       VPFVILGNKIDAPNAVSEAELRSALGLLNTTGSQRIEG-----QRPV----------EVF
CONSENSUS/80%    VPFlILGNKIDhP.AhSEsEL+.tLGLhphT.............+sl..........EVF
CONSENSUS/65%    VPFLILGNKIDAPsAlSEDELRuALGLhNTTsupth.s.....sRPV..........EVF
CONSENSUS/50%    VPFLILGNKIDAPsAlSEDELRuALGLhNTTsupth.s.....sRPV..........EVF


sar1_yeast       MCSVVMRNGYLEAFQWLSQYI----
CONSENSUS/80%    MCSlVh+.GYhEuFpWLuQYl.   
CONSENSUS/65%    MCSVVhRpGYGEGFKWLSQYI.   
CONSENSUS/50%    MCSVVhRpGYGEGFKWLSQYI.

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T