Consensus terms for the SEC14 domain

4437/1-0         EKPLIAKFYPQYYH----KTDKDGRPVYFEELGAVNL-----HEMNKVTSEERMLKNLVW
CONSENSUS/80%    ..t.h.hhh.t.........sppsp.lhh...t.............t.ht.pphhphhh.
CONSENSUS/65%    phphhtthh.sh........Dcpupslhh.hhtth...........pphs.pchhphhlh
CONSENSUS/50%    chcstptahsush......hD+cG+PVhlhpsuphs.........hpspspcchl+hhlt


4437/1-0         EYESVVQY-RLPACSRAAGHLVETSCTIMDLKGISISSA------YSVMSYVREASYISQ
CONSENSUS/80%    .h-thht...............t.hhhlhDhpsh..............ht.ht.hhphht
CONSENSUS/65%    hhEphhpt..........stt.pthhhlhDhcshsh............hphhpthhphhp
CONSENSUS/50%    hhEpslpp.........hssshsshshlhDhcGhshtp.........shssh+phlpllp


4437/1-0         N-YYPERMGKFYIINAPFG---FSTAFRLFKPFLDPVTVSKIFILG-------SSYQKEL
CONSENSUS/80%    t..asp.ltthhhlpssh....h.hhhphhp.hlp.thht+hhhh..............h
CONSENSUS/65%    s.taP-pltphhllpsPh...hh.shaphhpshlstphppKlhhht..........hppL
CONSENSUS/50%    c.pYPEpLppllllNsPt...hhpshaslh+sFLsscT+pKlphls........phtppL


4437/1-0         LKQIP--AENLPVKFGGKSE------------
CONSENSUS/80%    hp.ht...ptls..htu......         
CONSENSUS/65%    hphls...pplPtthGGp.p...         
CONSENSUS/50%    tcal-..pcpLPsphGGsss...         

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T