Consensus terms for the SH3 domain

O61080/1-59      GPEQARALYDFAA-------------ENPDELTFNEGAVVTVINKS--------------
CONSENSUS/80%    ....hhshhsats.............tt.tclshptu-hl.lhpp...............
CONSENSUS/65%    th.hshAlasapu.............ppss-LshppG-hlhllpp...............
CONSENSUS/50%    ssppspAlYDYsu.............psscELoFccGDllpllccs..............


O61080/1-59      -------------NPDWWEGELN------------------GQRGVFP-----ASYVELI
CONSENSUS/80%    .............tttWh.sp....................tp.GhhP.....tsalp.h
CONSENSUS/65%    .............sssWatupht..................sppGhhP.....ssalp.h
CONSENSUS/50%    .............cssWWcGcps.................tGcpGhhP.....usYVchh


O61080/1-59      P
CONSENSUS/80%    .
CONSENSUS/65%    .
CONSENSUS/50%    p

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T