Consensus terms for the SOCS domain

AB006968_1/1-44  VSRFMQVRSLQY---LCRFVIRQYTRI-DLIQKLPLPNKMKDYLQEKH
CONSENSUS/80%    ..t.p.s.SLQa...LCRhhl.thht....h.tlPlP.hhhpaLp.h.
CONSENSUS/65%    h.p.pps.SLQa...LCRhslpphsph.ttlpsLPLPthlpcaLpph.
CONSENSUS/50%    hsRhpplpSLQH...LCRhsIpssssh.splpsLPLPstl+-YLppap

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T