Consensus terms for the START domain

rhogap_rat/1-20  HFLQDCVDGLFKEVKEKFKGWVSYP-----TSEQAELSYKKVS-------------EGPP
CONSENSUS/80%    .h..t...t.ht.hh.t...W.................hhth..................
CONSENSUS/65%    .httpsttthhphhtsstttWhh..........pttttshpth.............tsps
CONSENSUS/50%    phpscsspshlppsssspcsWspss......ptcstpcshpphsss..........sucs


rhogap_rat/1-20  LRLWRATIEVPA--APEEILKRLLKEQHLWDVDLL-----------DSKVIEILDSQ---
CONSENSUS/80%    .+h.thh.......h...hh.t......tWpp.h.............hthlp.ht.s...
CONSENSUS/65%    h+hhshl.tss...hhtplhpsh.....pWcpsht...........tspslctlsss...
CONSENSUS/50%    hRstulVsssss.plsp-lhccsth.hhcWDcshs...........pspll-slsss...


rhogap_rat/1-20  ----TEIYQYVQNSMA--PHPA-RDYVVLRTWRTN-------LPRGACALLFTSVDHDRA
CONSENSUS/80%    ....s.l.h...t..h...h.s.R-hh.lR.hp..... .....tt.hhlh..ohp..t.
CONSENSUS/65%    ....sslhhhhsphhh..slss.R-hlhlRhh+p.... ....spsshslsstSlsp.pt
CONSENSUS/50%    ....uslpahssssss.sPlsP.RDaVhVRpp+p.... ....sccsalllssSlspsss


rhogap_rat/1-20  P------VAGVRVNVLLSRYLIEPCGSGK-----------SKLTYMCRADLRGHMP----
CONSENSUS/80%    ........thhRsphh.shhhhp..tts............sphhhl..h-hts.......
CONSENSUS/65%    s.......shlRschhsothhlpspsss............splsal.ps-lputh.....
CONSENSUS/50%    ss....psuhlRucphPSGhlIcssusGh...........o+lsalppsDLcGpsP....


rhogap_rat/1-20  EWYTKSFGHLCAAEVVKIRDSFSNQSTESKD
CONSENSUS/80%    p.hhp.hht.th..hhp....htthpt.t.p
CONSENSUS/65%    phhhcshhppshh.hhct..hhstlpptstp
CONSENSUS/50%    ctll+slhssuhspss+p..phAsLpcssp+

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T