Consensus terms for the TBC domain

Cec38h2_2        FWKQARAEPTIEEWRVLEAEVRRRDEEAFRAARARKAASPVREESCDVFEDPNEPTCSQH
CONSENSUS/80%    ...ths.phRs.lW.hh.t......................................tt.
CONSENSUS/65%    hppGlstphRs.lWphLhpt...t.................................pt.
CONSENSUS/50%    sppGlPsphRupVWplLhsspspstt...............................csp


Cec38h2_2        YDRENLITLFRAN--------------------------------------LHRIDKDVE
CONSENSUS/80%    apphhp.....tt.........................................lthDl.
CONSENSUS/65%    Ypphhpttt.ppp.........................................IphDlt
CONSENSUS/50%    Ycshhcpssspsppt.....................................ppIcpDls


Cec38h2_2        RCDRNLMFF---------------------------------------------------
CONSENSUS/80%    +ph....hh...................................................
CONSENSUS/65%    Rshsp.shap..................................................
CONSENSUS/50%    RThPspsaFpp.................................................


Cec38h2_2        ----------------SNKDNLESLRRVMYTYVRRNLE------------EGYTQGMCDL
CONSENSUS/80%    ....................h.ttL.plLhsashhp.p............hsYsQuhs.l
CONSENSUS/65%    ....................h.ppLhplLhsYuhhpsp............luYsQGhs.l
CONSENSUS/50%    .................tssspcsLpclLpuYulhssc............lGYsQGMshl


Cec38h2_2        LAPLLVTFE----------------------------------DEALTLECFSLLMLRQR
CONSENSUS/80%    hu.hhh.h.....................................ttsa.hh..lhtt..
CONSENSUS/65%    suslLhhh...................................pEtpuFhhhstlhpphh
CONSENSUS/50%    susLLlhh...................................sEpcAFhhlspLhpcht


Cec38h2_2        GKFP---------------------------------------------------QRPGM
CONSENSUS/80%    .......................................................t..th
CONSENSUS/65%    ..h....................................................sh.sh
CONSENSUS/50%    .phh.................................................p.shsul


Cec38h2_2        SKCLLNLRSLIQVV---------DPQIYALISDID-------------------------
CONSENSUS/80%    ....h.h.thlp...      ...splhthh.............................
CONSENSUS/65%    thphhhhpphlpph.      ...PcLhp+lpt...........................
CONSENSUS/50%    ptsttshspllcch.      ..hP-LapHLpp...........................


Cec38h2_2        ----YAQALSFAFRWFLLDFKRELSYECTYKVWEVIWAAQRLRITDDFAIFFGLATITNY
CONSENSUS/80%    .....ht..hhhh.hhh.hh.pth.ht.hhplhDhhhht.....t..hhh.hhhthht..
CONSENSUS/65%    ....thpsphashpWhhshFtpphPhphsh+laDhhhhp.....s.thhhthhlshlpht
CONSENSUS/50%    ....plssshauhpWhLolFscphPLchslRlWDhlas-.....usphlhplululLphp


Cec38h2_2        HDVLITNN--
CONSENSUS/80%    p..h.p....
CONSENSUS/65%    pphlhpht..
CONSENSUS/50%    cppLlpts..

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T