Consensus terms for the TFIIE domain 

A64397_pir/1-1   EKGFEVIDVLLEKGETTEEEIAKELGVKLNVVRKLLYKLYD--ARLVDYKRWKDEDTN--
CONSENSUS/80%    tchh.ll.hlhhpsthp---ltp.hthchp.lRpllhtLhs..hhhhchpptps.psp..
CONSENSUS/65%    tcthhllctLhcpuphp---ltphlthchpplRplLhtLhs..hhhhch++pps.csp..
CONSENSUS/50%    uEssllLDsLh+cGsloEEDLuclLul+pspLR+lLtsLc--+hllsca+Rc+cc-o+..


A64397_pir/1-1   ---------------------------WYSYTWLPTLEKLPYVVKKKINELIKDLEKKLE
CONSENSUS/80%    ...........................hhpaha.hphcph.psl+h+hpchhc+Lcpc.p
CONSENSUS/65%    ...........................hhpYaahlshcplssll+h+lcchhc+Lcpc.c
CONSENSUS/50%    ...........................ahpYYWhIsYc+ll-VVKaKlc+hl+RL+ccL-


A64397_pir/1-1   FEKNNMFFFCPN--CNVRFTFEEAMDYG--------FSCPGCGNMLQEFDNSELIKDLEE
CONSENSUS/80%    .pssp..ahCss..C..pao..EA.ph........ FpCshCst.l...-ss...cchcp
CONSENSUS/65%    tcosphhahCss..C..+aoh.EAhplh....... FpCshCss.lpt.-suhshc-hcc
CONSENSUS/50%    c-TsssaYpCPN..CssKaTaLEAscLss..s.p. FoCPpCGupL-E-Dsucsl+-l+-

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T