Consensus terms for the TOPRIM domain

AB50173|CAB501   SALMIVESPNKARTIASFFGQPSKRRIG-------------------ELVAYEVSIGDKM
CONSENSUS/80%    p.lhlsEt..pshthtphh...................... ..................
CONSENSUS/65%    ptllllEu.tcshsltphhh..................... ..................
CONSENSUS/50%    cslllVEussDstslpphts..................... .................t


AB50173|CAB501   LTILASGGHMFDLVTTEGYHGVL-ILKDDGKPYYVPVYDTIKRCRDCGHQFVDWEQK-GV
CONSENSUS/80%    ..hhs.hGth..................................................
CONSENSUS/65%    hhshushGph..................................................
CONSENSUS/50%    tplsustGpl..................................................


AB50173|CAB501   CPKC-GSRNVHDALENVKAMRELALEV----DEILIGTDPDTE---------GEKIAWDI
CONSENSUS/80%    ..............t.hp.ltphh.t.......lhlhhDsDtt.........Gpthshph
CONSENSUS/65%    ............tpphlphlpchtpp.......lllshDsDpt.........Gcthuhcl
CONSENSUS/50%    ...........tsccplctl+ctscc.....ppVllusDsDcE.........G-sluhcl


AB50173|CAB501   RNVLSPYTP
CONSENSUS/80%    hp.ht....
CONSENSUS/65%    hphhpshsh
CONSENSUS/50%    hchlpspst

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T