Consensus terms for the VKc domain 

gi|33862449|ref  ------LKWPRIAMAVLATVGLIDTGSITLHRWGWIGS--------LSCPG-------GN
CONSENSUS/80%    ..........hhhhhhhshhGhh.ohhhhh.phth...........s.Csh........h
CONSENSUS/65%    .......t.hthhhhhhuslGlhhohhlsh.chphhp.........shCshs.......h
CONSENSUS/50%    ......sphsshlllllullGLlsSsYLolcKlshtpt.......hssCsls......ss


gi|33862449|ref  EGCDKVLNSAWGTLFQGDGVS----------------------IPLSLLGFLAYFVILVM
CONSENSUS/80%    hsCstVhpS..uthhs...........................hP.shhGhhhahhhhhh
CONSENSUS/65%    huCspVhpS.auplhG...........................hP.slhGhhhasshlhh
CONSENSUS/50%    loCucVhsSsaAslFG...........................lPsullGlluYslllsl


gi|33862449|ref  AVLPLLPG---LSENRADLSRRTWWGLFAISCGMAVFSLILIGLMVFKID-AFCFFCVLS
CONSENSUS/80%    uhh.h...............thhhhhhhhh.hhhhhhshaLhh..hhhlt.shC.hChhs
CONSENSUS/65%    uhh.h...............phhhhhlhhhshsssshshaLhah.hahlt.shChaChss
CONSENSUS/50%    ulhshhh.........sth.chhhhsLhluulsuslaShYLhaltlatIp.AlClYClls


gi|33862449|ref  AALSICLLVLSLIGG
CONSENSUS/80%    hhhth.hhhh.h.h.
CONSENSUS/65%    hhhshshhhlshhth
CONSENSUS/50%    allolsLhlLsstts

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T