Consensus terms for the WD40 domain

PKWA_THECU/1-40  SGEALHTFE---------------GHTD-------------WVRAVAFSPDG--------
CONSENSUS/80%    t.t.h..h.................ptt..............l.shtht.p.........
CONSENSUS/65%    stphhtphp...............sHpt..............ltslshssss........
CONSENSUS/50%    sspslpslp...............uHss.............sVsslsassss........


PKWA_THECU/1-40  ----------------------------------ALLASGSD--DRT-------IRLWD
CONSENSUS/80%    ...................................hhhsss...st........lhhap
CONSENSUS/65%    ..................................phlhouut..Dtp.......lplWs
CONSENSUS/50%    ..................................phlsouop..Dss.......l+lW-

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T