Consensus terms for the WHy domain

Q9RUL2           LTSFSLPAPGRAAVAGVRLELNVDNPNPLPVRLVQLAGVLVLDG-QEAG-TVTVPD-IRL
CONSENSUS/80%    ....hp...ht..phphhhphpltNPsshsl.hpshth.l.hss.h.hs.pu...p.hpl
CONSENSUS/65%    ph.thchh.sph.phchhhplclpNPNshslslsslshtltlsu.hplu.pGp..psspl
CONSENSUS/50%    slsslchtsssstclclhlcl+VpNPNssPIslsslshsLplNG.tplu.sGssscsusl


Q9RUL2           PGQGRARQVAQLTLPVTFKTATTFLNIARG---QEVSYRLD-GTLT
CONSENSUS/80%    ...upthl.lslph.....h.t.h.th.tt...tthshplphthhh
CONSENSUS/65%    .tpupshlslslpl.sh..h.phh.thtps...tphshplchthth
CONSENSUS/50%    sspucsslslPlsl.stpttsphtpclsss...pclsYclcssLss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T