Consensus terms for the WWE domain

KIAA0937/1       SAVVVWEWLNE----HGRWRPYS-------PAVSHHIEAVVRAG-------PRAGGSVVL
CONSENSUS/80%    tt.hhW.a.st.....stWh.as........tspp.lEpsat.........tp.ht.h.h
CONSENSUS/65%    spthhW.a.sc....pusWhtYs........psscpIEpuaptt.......pphhphhhh
CONSENSUS/50%    ssshlWpapuc....pGsWasYc.......scssccIEcAasps.......csssclslt


KIAA0937/1       GQVD--SRLAPYIIDLQSMNQFRQDTG-----TLRPVRRNYYDPSSA
CONSENSUS/80%    u........hsYhlshpthhQhppspt......h+.l+R.h.s....
CONSENSUS/65%    G........hsYhlshpsMsQhppsss......pRtl+Rshhss.sh
CONSENSUS/50%    G........psYllDFpsMsQhspsou......pRsV+Rsttsshst

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T