cov    pid   1 [        .         .         .         .         :         .         .         . 80 
 1 GYRA_CAMJE/1-4 100.0% 100.0%     VDIENSIKSSYLDYSMSVIIGRALPDARDGLKPVHRRILYAMQNDEAKSRTDFVKSARIVGAVIGRYHPHGDTAVYDALV    
 2 GYRA_CAMFE/1-4 100.0%  79.0%     IDVEDSIKASYLDYSMSVIIGRALPDARDGLKPVHRRILYAMNDLGVGSRSPYKKSARIVGDVIGKYHPHGDTAVYDALV    
 3 AE001496_3/1-4 100.0%  70.0%     VGIDSSIEESYLAYSMSVIIGRALPDARDGLKPVHRRILYAMHELGLTSKVAYKKSARIVGDVIGKYHPHGDTAVYDALV    
 4 O84192/1-473   100.0%  53.8%     KNLEEEMKESYLRYSMSVIISRALPDARDGLKPSQRRILYAMKQLNLTPGVKHRKCAKICGDTSGDYHPHGESVIYPTLV    
 5 GYRA_ERWCA/1-5 100.0%  56.0%     VNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMSVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYETIV    
 6 GYRA_HAEIN/1-5  99.8%  53.1%     VNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFSMDREGNTANKKYVKSARVVGDVIGKYHPHGDSAVYDTIV    
 7 GYRA_PSEAE/1-5 100.0%  55.5%     VNIEDELKQSYLDYAMSVIVGRALPDARDGLKPVHRRVLYAMSELGNDWNKPYKKSARVVGDVIGKYHPHGDTAVYDTIV    
 8 O86092/1-506    99.8%  54.8%     ISLEDEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHELSNDWNRPYKKSARIVGDVIGKYHPHGDTAVYDTIV    
 9 GYRA_NEIGO/1-5 100.0%  51.4%     VSLEDEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELKNNWNAAYKKSARIVGDVIGKYHPHGDSAVYDTIV    
10 Q47968/1-480    99.3%  54.6%     ARIEDEMEQSYIDYAMSVIAGRALPDVRDGLKPVHRRILYAMHQAGVTSNSSHRKSSSIVGETMGDYHPHGDSAIYDTLA    
11 O24814/1-472   100.0%  53.7%     VNLTSEMKTSFIDYAMSVIVSRALPDVRDGLKPVQRRILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMV    
12 GYRA_BACS5/1-4  99.8%  58.4%     INISQEMKTSFMDYAMSVIVSRALPDVRDGMKPVHRRILYAMNELGMTSDKAYKKSARIVGEVIGKYHPHGDSAVYETMV    
13 SARECF_3/1-473 100.0%  57.1%     RNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMV    
14 GYRA_CLOAB/1-4 100.0%  60.4%     VDISSEMKKCYIDYAMSVIVSRALPDVRDGLKPVHRRILYSMHELGLTPEKGYRKCARIVGDVLGKYHPHGDSSVYGALV    
15 MG09251_4/1-47  99.8%  52.4%     ISLANELERSFMEYAMSVIVARALPDARDGLKPVHRRVLYGAYIGGMHHDRPFKKSARIVGDVMSKFHPHGDMAIYDTMS    
16 Q55738/1-477   100.0%  55.6%     TDLRNEMSQSYLEYAMSVIVGRALPDARDGLKPVHRRILYAMYELGLTPDRPFRKCARVVGEVLGKYHPHGDTAVYDALV    
17 Q59784/1-498    99.8%  51.4%     VSIAEEMKTAYLDYAMSVIVSRAIPDLRDGLKPVHRRILYAMHETGNTHDKPYRKSARPVGDTMGKYHPHGDGAIYDALV    
18 GYRA_RICPR/1-4  99.8%  53.8%     VNIEDEMKVSYLDYAMSVIVSRAIPDVRDGLKPVHRRIIYSMYEAGNHASKPYRKSARIVGDVMGKYHPHGDSAIYDSLV    
19 GYRA_MYCTU/1-4 100.0%  51.4%     VDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLV    
20 GYRA_STRCO/1-4  99.8%  53.2%     VGLETEMQRSYLDYAMSVIVSRALPVVRDGLKPVHRRVLYAMYDGGYRPERGFYKCARVVGDVMGNYHPHGDSSIYDALV    
21 GYRA_BORBU/1-4 100.0%  54.0%     VRIEDEIKTSYLNYAMSVIVSRALPDVRDGLKPVHRRILYSMYEMGLRSDKAFKKAGRIVGDVLGKYHPHGDQSIYDALV    
22 GYRA_TREPA/1-4 100.0%  49.9%     ISIETEVKRAYIDYSMSVIVSRALPDVRDGLKPVHRRILYAMEEKGLRFSGPTRKCAKIVGDVLGSFHPHGDASVYDALV    
23 GYRA_SYNY3/1-4 100.0%  48.8%     TDLHEEMERSYLEYAMSVIVGRALPDVRDGLKPVHRRILYAMYELGLTPDRPFRKCARVVGDVLGKYHPHGDQSVYDALV    
24 O67108/1-472    99.6%  54.4%     IPIEEEVKQAYIDYAMSVIVGRAIPDVRDGLKPVQRRILYSMYEMGLLPDKPFKKSARIVGETLGKYHPHGDQAVYEALV    
25 O29785/1-466    98.9%  55.4%     RDISEELKSSYIDYAMSVIVGRALPDVRDGLKPVQRRILYAMYEMGLFSNRPYRKSARIVGEVLGKYHPHGDSAVYDALV    
26 O50510/1-474   100.0%  47.6%     IDVVDEMQGSFLEYAYSVIYSRALPDARDGLKPVHRRIVYQMNEMGLRPERGYVKCARVVGEVMGKLHPHGDASIYDALV    
27 PARC_ECOLI/1-4  98.5%  43.2%     LALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMV    
28 PARC_HAEIN/1-4  98.5%  43.9%     MPLRTFTEKAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKYKKSARTVGDVLGKFHPHGDSACYEAMV    
29 PARC_NEIGO/1-4  99.3%  41.0%     LMLGRYAERAYLEYAMSVVKGRALPEVSDGQKPVQRRILFAMRDMGLTAGAKPVKSARVVGEILGKYHPHGDSSAYEAMV    
30 PARC_CAUCR/1-4  99.1%  46.8%     EPLTEALSRRYLAYALSTIGSRALPDVRDGLKPVHRRVLYAMSNMRLNPDAAARKCAKVVGEVMGNFHPHGDASIYDALV    
31 E1342381/1-471  99.1%  50.5%     IDFGNALSERYLAYALSTIMSRSLPDVRDGLKPVHRRLLYAMLQLRLEPNSGYKKCARVVGDVIGKYHPHGDVAVYDTLV    
32 PARC_MYCGE/1-4  99.6%  41.3%     KAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPHGDSSIYDAII    
33 PARC_MYCPN/1-4 100.0%  41.5%     QAIEDVFAFSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMYQMGLKPTSPYKKSARAVGEIMGKYHPHGDASIYDAIV    
34 G3513507/1-476 100.0%  41.5%     KNMADIMSDRFGRYSKYIIQQRAIPDARDGLKPVQRRILYSMWNLHLKNSEPFKKSARIVGDVIGRYHPHGDSSIYEALV    
35 PARC_BACSU/1-4  99.8%  49.7%     LPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMV    
36 PARC_STAAU/1-4  99.8%  46.2%     LSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDSSVYEAMV    
37 PARC_STRPN/1-4  99.8%  45.3%     MSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMV    
38 PARC_BORBU/1-4  93.8%  25.8%     MDIRTVLKDNFLQYSSYVIKDRAIASVVDGFKPVQRRIIHSLFEMHDGN---FHKVANVVGNTM-KYHPHGDTSIYEALV    
39 O84667/1-455    93.8%  24.8%     SDLSDLFKTHFTQYASYVILERAIPHVLDGLKPVQRRLLWTLFRMDDGK---MHKVANIAGRTM-ALHPHGDAPIVEALV    
40 TOP5_BPT4/1-44  94.9%  22.2%     RDLKSIIDNEALAYAMYTVENRAIPNMIDGFKPVQRFVIARALDLARGNKDKFHKLASIAGGVADLGYHHGENSAQDAGA    
41 O24308/1-483    90.7%  15.3%     INYKDFVNKELILFSR-ADLFG-------------------SFKKKLYK-EIKVAQFIGYVSEHSAYHHG-EQSLASTII    
42 Q23670/1-511    95.1%  15.8%     VTFKDFVNRELVLFSN-LDNERSIPCLVDGFKPGQRKVLFACFKRADKR-EVKVAQLAGAVAEISAYHHG-EQSLMGTIV    
43 P90520/1-499    92.9%  14.1%     ITYPDFINKELIHYSW-AANLRSIPSLIDGLKPGQRKILFASFKRRLTN-EIKVSQLSGYVAEQTSYHHG-EQSLNSTIV    
44 TOP2_TRYCR/1-4  93.2%  15.4%     LTVPDFVHKEMVHFAL-AGNARALAHAVDGLKPSQRKILWAIMRRSGNE-SAKVAQLSGYISEVSAFHHG-EMSLQETII    
45 O41065/1-434    91.2%  18.9%     VPVPDFIDKELILFSR-YDLERSIPSVVDGFKPSQRKVLYCAFKRNLTS-DVKVAQFSGYVAEHSAYHHG-EVSLQGTIV    
46 TOP2_ARATH/1-5  95.4%  16.4%     VTYSDFVNKELILFSM-ADLQRSIPSMVDGLKPGQRKILFVAFKKIARK-EMKVAQLVGYVSLLSAYHHG-EQSLASAII    
47 TOP2_SCHPO/1-4  93.8%  16.8%     IPIDDFINRELIQFSM-ADNIRSIPSVVDGLKPGQRKVVYYCFKRNLVH-ETKVSRLAGYVASETAYHHG-EVSMEQTIV    
48 TOP2_PLAFK/1-4  95.1%  18.2%     LSYYDFVNKELIYYSR-YDTERSIPNIMDGWKPGQRKVLYGCFKRNLRN-ECKVAQLVGYIAEHSAYHHHGESSLQQTII    
49 O59864/1-494    95.1%  17.0%     ISYTDFINNELIQFSM-ADNLRSIPSMVDGMKPGQRKVMYTVMKRNIKK-DVKVLDLTGQVFSLTAYHHG-DASMHQTII    
50 TOP2_DROME/1-5  95.1%  15.3%     ITYADFINLELVLFSN-ADNERSIPSLVDGLKPGQRKVMFTCFKRNDKR-EVKVAQLSGSVAEMSAYHHG-EVSLQMTIV    
51 TOP2_CRIFA/1-4  93.2%  16.9%     LTIGDFVHKEMVHFAL-VGNARAIPHCVDGLKPSQRKILWAMLKRHSSE-AAKVAQLSGYISEVSSFHHG-EASLQETIV    
52 D1034930/1-511  94.7%  15.4%     IPISDFINKELILFSL-ADNVSSIPSVLDGFKPGQRKVLYTCFKKNLTT-EKKVANLAPAVSDYTAYHHG-EQALVQTII    
53 TP2B_MOUSE/1-4  95.1%  17.1%     LTYNDFINKELILFSN-SDNERSIPSLVDGFKPGQRKVLFTCFKRNDKR-EVKVAQLAGSVAEMSAYHHG-EQALMMTIV    
54 TOP2_YEAST/1-5  94.7%  15.4%     IPISDFINKELILFSL-ADNIRSIPNVLDGFKPGQRKVLYGCFKKNLKS-ELKVAQLAPYVSECTAYHHG-EQSLAQTII    
55 TP2A_MOUSE/1-4  95.1%  17.3%     LTYNDFINKELILFSN-SDNERSIPSMVDGLKPGQRKVLFTCFKRNDKR-EVKVAQLAGSVAEMSSYHHG-EMSLMMTII    
56 CER05D3_1/1-48  93.8%  16.1%     ARMSDGV-EDLQRFE--SQRIQSIPSLIDGLKPSQRKILWTLLNNMDESTEIKVSQLAGAVAHRQSYHHG-EESLVRTII    
57 TOP2_CANAL/1-5  94.5%  14.8%     IPISDFINKEFILFSM-SDNVRSIPSVLDGFKPGQRKVLYGCFKKKLRS-EIKVAQLAGYVSENTGYHHG-EQSLVQTII    
58 O16140/1-511    94.7%  16.7%     VTYSDFVNLELVLFSN-GDNVRSIPSMIDGLKPGQRKVIFTCIKRNDKR-EVKVAQLAGSVAEHSAYHHG-EQSLAMTIV    
59 O61078/1-458    92.9%  14.1%     LTIPEFVHKQMIHFVH-LGNERGIPHCFDGLKPWQRKILWAMLKRSSSE-AAKVAHLSGYISEASAFHHG-EASMQETMI    
   consensus/100%                   ..h.p.h..th..a.......t...............................h......h.....ha.t.-.sh..sh.    
   consensus/90%                    hsh.p.httthh.au..h...RulPphhDGhKPspR+llash.p.t.t..t.hhtphthhst.hstaH.t.-.uh.tshl    
   consensus/80%                    hshtp.hppphl.auh.s..tRulPshhDGhKPspR+lLash.pht.p..t.hhtphthhst.hutYH.t.-tulhpshl    
   consensus/70%                    lslp-.hppphlpYuh.sh.sRulPshhDGLKPspR+lLauhhchs.p..pshhpphphssshhupYH.t.-sulhcslV    

                     cov    pid  81          .         1         .         .         .         .         :         . 160
 1 GYRA_CAMJE/1-4 100.0% 100.0%     RMAQDFS--MRYPSITGQGNFGSI--DGDSAAAMRYTEAKMSKLSH-ELLKDIDKDTVDFVPNYDGSESEPDVLPSRVPN    
 2 GYRA_CAMFE/1-4 100.0%  79.0%     RMAQNFS--MRVPAVDGQGNFGSV--DGDGAAAMRYTEARMTVLAE-ELLRDLDKDTVDFIPNYDDSLSEPDVLPARVPN    
 3 AE001496_3/1-4 100.0%  70.0%     RMAQDFS--MRLELVDGQGNFGSI--DGDNAAAMRYTEARMTKASE-EILRDIDKDTIDFVPNYDDTLKEPDILPSRLPN    
 4 O84192/1-473   100.0%  53.8%     RMAQDWA--MRYPLVDGQGNFGSI--DGDPAAAMRYTEARLTHSAI-FLLEDLDKDTVDMVPNYDETKYEPVVFPSKFPN    
 5 GYRA_ERWCA/1-5 100.0%  56.0%     RMAQPFS--LRYMLVDGQGNFGSI--DGDSAAAMRYTEIRMSKIAH-ELLADLEKETVDFVPNYDGTEQIPDVMPTRIPN    
 6 GYRA_HAEIN/1-5  99.8%  53.1%     RMAQPFS--LRYMLVDGQGNFGSI--DGDAPAAMRYTEVRMQKITQ-ALLTDLDKETVNFSPNYDGELMIPDVLPTRIPA    
 7 GYRA_PSEAE/1-5 100.0%  55.5%     RMAQPFS--LRYMLVDGQGNFGSV--DGDNAAAMRYTEVRMAKLAH-ELLADLEKETVDWVPNYDGTEQIPAVMPTKIPN    
 8 O86092/1-506    99.8%  54.8%     RMAQDFS--LRYMLVDGQGNFGSV--DGDNAAAMRYTEIRMAKIAH-ELLADIDKETVDFGPNYDGSEHEPLIMPARIPN    
 9 GYRA_NEIGO/1-5 100.0%  51.4%     RMAQNFA--MRYVLIDGQGNFGSV--DGLAAAAMRYTEIRMAKISH-EMLADIEEETVNFGPNYDGSEHEPLVLPTRFPT    
10 Q47968/1-480    99.3%  54.6%     RMAEDFS--MRYPLVDGQGNFGSV--DGDPPAAMRYTEARMSPIAE-ELLDDIDKDTVDFQSNYDDRKQEPTVLPSSFPN    
11 O24814/1-472   100.0%  53.7%     RMAQWWS--YRYMLVDGHGNFGSM--DGDGAAAQRYTEARMSKIAL-EMLRDLNKNTVDFQDNYDGSEREPIVLPSRIPN    
12 GYRA_BACS5/1-4  99.8%  58.4%     RMAQDFS--YRYMLVDGHGNFGSI--DGDAAAAMRYTEARMSKISM-ELVRDINKDTIDYQDNYDGSEKEPVVMPSRFPN    
13 SARECF_3/1-473 100.0%  57.1%     RMAQDFS--YRYPLVDGQGNFGSM--DGDGAAAMRYTEARMTKITL-ELLRDINKDTIDFIDNYDGNEREPSVLPARFPN    
14 GYRA_CLOAB/1-4 100.0%  60.4%     RLAQDFN--LRYTVVDGHGNFGSV--DGDSAAAMRYTEAKMNKIAL-EMVRDIGKNTVDFIPNFDGEEKEPVVLPSRFPN    
15 MG09251_4/1-47  99.8%  52.4%     RMAQDFS--LRYLLIDGHGNFGSI--DGDRPAAQRYTEARLSKLAA-ELLKDIDKDTVDFIANYDGEEKEPTVLPAAFPN    
16 Q55738/1-477   100.0%  55.6%     RMAQDFS--MREPLIDGHGNFGSV--DNDPPAAMRYTESRLRPLSTNSLLRDIEAETVDFIDNFDGSQQEPTVLPARIPQ    
17 Q59784/1-498    99.8%  51.4%     RMAQPFS--MGLKLLDGQGNFGSM--DGDNAAAMRYTEVRMDKPAA-FLLADIDKDTVDFQDNYDGKDREPTVLPARFPN    
18 GYRA_RICPR/1-4  99.8%  53.8%     RMAQDFS--LRLPLVDGQGNFGSM--DGDAAAAMRYTESRMAKVAH-KLVEDIDKGTVSFNINYDGSEEEPSVLPAMFPN    
19 GYRA_MYCTU/1-4 100.0%  51.4%     RMAQPWS--LRYPLVDGQGNFGSP--GNDPPAAMRYTEARLTPLAM-EMLREIDEETVDFIPNYDGRVQEPTVLPSRFPN    
20 GYRA_STRCO/1-4  99.8%  53.2%     RLAQPWS--MRMPLVDSNGNFGSP--GNDPAAAMRYTECKMAPLSM-EMVRDIDEETVDFTDNYDGRSQEPTVLPARFPN    
21 GYRA_BORBU/1-4 100.0%  54.0%     RLAQDFS--LRYPVIRGQGNFGSI--DGDPPAAMRYTEAKMEKITE-YIVKDIDKETVNFKSNYDDSLSEPEIMPSSFPF    
22 GYRA_TREPA/1-4 100.0%  49.9%     RLGQDFS--LRYPVIHPQGNFGTI--GGDPPAAYRYTEAKMARIAE-SMVEDIKKETVSFVPNFDDSDVEPTVLPGRFPF    
23 GYRA_SYNY3/1-4 100.0%  48.8%     RMVQDFS--SRYPLLAGHGNFGSV--DNDPPAAMRYTETRLAPIAMGAMLEGISEAIVDFTGNFDNSQEEPTVVPAQLPL    
24 O67108/1-472    99.6%  54.4%     RMAQDFT--MRYPLIIGQGNFGSI--DGDPAAQMRYTEAKLSPLAV-EMLTDIDKDTVDFQPNFDDTLMEPEVLPSKFPN    
25 O29785/1-466    98.9%  55.4%     RMAQDFV--MRYPLVDGQGNFGSI--DGDSPAAMRYTEARLTKIAE-EMLADIGKNTVDFMPNFDATLKEPVVLPSKIPN    
26 O50510/1-474   100.0%  47.6%     RMAQSFS--MRVPLVDGHGNFGSLG-NDDPPAAMRYTECRMAEAAG-LMTESIDEDTVDFAPNYDGQEQEPVALPAAFPN    
27 PARC_ECOLI/1-4  98.5%  43.2%     LMAQPFS--YRYPLVDGQGNWGAPD-DPKSFAAMRYTESRLSKYSE-LLLSELGQGTADWVPNFDGTLQEPKMLPARLPN    
28 PARC_HAEIN/1-4  98.5%  43.9%     LMAQPFS--YRYPLVDGQGNWGAPD-DPKSFAAMRYTESRLSKISE-ILLNELGQGTVDYQPNFDGTLAEPQYLPARLPH    
29 PARC_NEIGO/1-4  99.3%  41.0%     RMAQDFT--LRYPLIDGIGNFGSR--DGDGAAAMRYTEARLTPIAE-LLLSEINQGTVDFMPNYDGAFDEPLHLPARLPM    
30 PARC_CAUCR/1-4  99.1%  46.8%     RLAQEFS--QRIPLVEGQGNFGNI--DGDSAAAMRYTECKMTEAAM-LLLDGIDEDAVDFRPTYDGQDEEPVVLPSGFPN    
31 E1342381/1-471  99.1%  50.5%     RLAQHFS--LRYPLIDGQGNFGSI--DGDNAAAMRYTESRMTEICM-LLMEDIDKDTVDFRSTYDDSDLEPVIMPASFPN    
32 PARC_MYCGE/1-4  99.6%  41.3%     RMSQSWK--NNWTTVSIHGNNGSV--DGDNAAAMRYTETRLSLYGF-ELLKDIDKKLVSFINNFDDSEKEPTVLPTLLPN    
33 PARC_MYCPN/1-4 100.0%  41.5%     RMSQAWK--NNLTTISIHGNNGSI--DGDNAAAMRYTEARLSPYGF-ELLKDIEKQLVPFVNNFDDSEVEPSVLPTLLPN    
34 G3513507/1-476 100.0%  41.5%     RMAQDWK--SNFPLIEMHGNKGSI--DDDPAAAMRYTESRLEKISE-LMLKDLDRKVVKMAPNFDDSEYEPIVLPALFPN    
35 PARC_BACSU/1-4  99.8%  49.7%     RMSQDWK--VRNVLIEMHGNNGSI--DGDPPAAMRYTEARLSPIAS-ELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPN    
36 PARC_STAAU/1-4  99.8%  46.2%     RLSQDWK--LRHVLIEMHGNNGSI--DNDPPAAMRYTEAKLSLLAE-ELLRDINKETVSFIPNYDDTTLEPMVLPSRFPN    
37 PARC_STRPN/1-4  99.8%  45.3%     RMSQNWK--NREILVEMHGNNGSM--DGDPPAAMRYTEARLSEIAG-YLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFPN    
38 PARC_BORBU/1-4  93.8%  25.8%     NIANKD------LFIEKQGNFGNLF-TGDPASASRYIECRLTPLAF---DVLYSKEITIYESSYDGRNNEPLLYPAKIPV    
39 O84667/1-455    93.8%  24.8%     VLANKG------FLIETQGNFGNPL-TGDPHAAARYIEARLSPLAK---EVLFNTDLMTFHDSYDGREQEPDILAAKIPL    
40 TOP5_BPT4/1-44  94.9%  22.2%     LMANTWN--NNFPLLDGQGNFGSR--TVQKAAASRYIFARVSKNFY----NVY-KDTEYAPVHQDKEHIPPAFYLPIIPT    
41 O24308/1-483    90.7%  15.3%     GMAQDFVGSNNINLLKPNGQFGTCNLGGKDHASARYIYTELSPVTR-CLFHEHDDKLLEYLNE-DGKSIEPNWYMPIIPL    
42 Q23670/1-511    95.1%  15.8%     NLAQDYVGSNNINLLLPIGQFGTRLQGGKDSASARYIFTQLSPVTR-TLFPAHDDNVLRFLYE-ENQRIEPEWYCPIIPM    
43 P90520/1-499    92.9%  14.1%     KMAHNFVGSNNLPLLTPSGQFGTRLQGGSD-SASARYILQLEPVGT-LPFNELDDPLLNYLEE-EGESIQPDYYIPIIPM    
44 TOP2_TRYCR/1-4  93.2%  15.4%     KMAQNFTGGNNINLLIPEGQFGSRQQLGNDHAAARYIFTKLSSLAR-ILFPSEDEPLLDYVTE-EGQQVEPNHYVPILPL    
45 O41065/1-434    91.2%  18.9%     NLAQDYVGSNNINWLLPEGQFGSRLQGGKDHASARYIFTKLNPKTR-QVFVDTDDNLLKYLYD-DGDKIEPECYVPIIPS    
46 TOP2_ARATH/1-5  95.4%  16.4%     GMAQDYVGSNNINLLLPNGQFGTRTSGGKDSASARYIFTKLSPVTR-ILFPKDDDLLLDYLNE-DGQRIEPTWYMPIIPT    
47 TOP2_SCHPO/1-4  93.8%  16.8%     NLAQNFVGSNNINLLMPNGQFGTRSEGGKNASASRYLNTALSPLAR-VLFNSNDDQLLNYQND-EGQWIEPEYYVPILPM    
48 TOP2_PLAFK/1-4  95.1%  18.2%     NMAQTFVGSNNINFLEPCGQFGSRKEGGKDASAARYIFTKLASSTR-SIFNEYDDPILKYLNE-EGQKIEPQYYIPVIPT    
49 O59864/1-494    95.1%  17.0%     GLAQDFVGSNNVNTLEPSGNFGSRLKGGADASSARYIHTRLSPFAR-KIFHPHDDPILKYLED-DGKEIEPWVYVPVVPM    
50 TOP2_DROME/1-5  95.1%  15.3%     NLAQNFVGANNINLLEPRGQFGTRLSGGKDCASARYIFTIMSPLTR-LIYHPLDDPLLDYQVD-DGQKIEPLWYLPIIPM    
51 TOP2_CRIFA/1-4  93.2%  16.9%     KMAQNFTGGNNINLLVPEGQFGSRQQLGNDHAAPRYIFTKLSRFAR-LLFPEDDDPLLDYIDE-EGTMVEPNHYVPILPL    
52 D1034930/1-511  94.7%  15.4%     GMAQNFVGTNNIYFLKPNGAFGTRATGGKDAAAARYIYTELNKIAR-KVFHPADDPLFRYVQE-DEKTVEPEWYLPVVPM    
53 TP2B_MOUSE/1-4  95.1%  17.1%     NLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLAR-LLFPAVDDNLLKFLYD-DNQRVEPEWYIPIIPM    
54 TOP2_YEAST/1-5  94.7%  15.4%     GLAQNFVGSNNIYLLLPNGAFGTRATGGKDAAAARYIYTELNKLTR-KIFHPADDPLYKYIQE-DEKTVEPEWYLPILPM    
55 TP2A_MOUSE/1-4  95.1%  17.3%     NLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLAR-LLFPPKDDHTLRFLYD-DNQRVEPEWYNPINTM    
56 CER05D3_1/1-48  93.8%  16.1%     RMGQTFCGSSNLPLLQPIGQFGTRHEGGNDAASARYIFTALAPTTR-LLFPQADDDLLQKNVE-EGMVVEPT-LCPIVPL    
57 TOP2_CANAL/1-5  94.5%  14.8%     GLAQNFVGSNNINVLKPNGSFGSRAAGGKDFSAARYIFTELSEITR-KIFNPLDDPLYTYVQD-DEQTVEPEWYLPVLPM    
58 O16140/1-511    94.7%  16.7%     NLAQNYVGSNNINLLEPRGQFGTRLSGGKDSASPRYIFTLMSPLTR-LIFHPHDDPLLVHEFE-DNQKIEPVYYLPIIPM    
59 O61078/1-458    92.9%  14.1%     KMAQNFTGGNNINLLVPEGQFGSRQQLGNVPEAPRYIFTKLRKVAR-LLFCCEDDPVLDYIVD-DGETVEPNQYVPILPL    
   consensus/100%                   .hsp..........l...Gt.Gs....s...tt.thh...ht............t.h..h..p.-t....P..h.s..s.    
   consensus/90%                    thuQsa....ph.hl..pGphGoh..ssps.uu.RYh.stht.hs...hh..hpc.hhpa..p.-sp..EP.hh.shhP.    
   consensus/80%                    phAQsas...ph.llpspGpFGoh..sGcssAAhRYh.schs.hs...hhtthsc.hlpa..p.Dsp..EP.hhsshhP.    
   consensus/70%                    phAQsFs...phsLlcspGsFGoh..sGcssAAhRYh.s+hs.lut..lhpsh-cphlcahss.DspphEP.hhsshhP.    

                     cov    pid 161          .         .         .         2         .         .         .         . 240
 1 GYRA_CAMJE/1-4 100.0% 100.0%     LLLNGSSGIAVGMATNIPPHSLNELIDGLLYLLDNKDAS----LEEIMQFIKGPDFPTGGIIYGKKG-IIEAYRTGRGRV    
 2 GYRA_CAMFE/1-4 100.0%  79.0%     LLLNGSSGIAVGMATNIPPHSLDELVNGLLTLLDDKEVG----LEDIMTHIKGPDFPTGGIIFGKKG-IIEAYKTGRGRI    
 3 AE001496_3/1-4 100.0%  70.0%     LLVNGANGIAVGMATSIPPHRIDEIIDALAHVLGNPNAE----LDKILEFVKGPDFPTGGIIYGKAG-IVEAYKTGRGRV    
 4 O84192/1-473   100.0%  53.8%     LLCNGSSGIAVGMATNIPPHNLGELIEATLLVLANSQTS----IEDILEVMPGPDFPTGGIICGTEG-IRSTYYTGRGKL    
 5 GYRA_ERWCA/1-5 100.0%  56.0%     LLVNGSSGIAVGMATNIPPHNLTEVVNGCLAYIDDENIS----LEGLMEHIKGPDFPTAAIINGRRG-IEEAYRTGRGKI    
 6 GYRA_HAEIN/1-5  99.8%  53.1%     LLANGSSGIAVGMATNIPPHNLNEVLNGCLAYIDKNEIT----IDELMQHIPGPDFPTAALINGRKG-IEEAYRTGRGKV    
 7 GYRA_PSEAE/1-5 100.0%  55.5%     LLVNGSSGIAVGMATNIPPHNLGEVIDGCLALMDNPDLT----VDELMQYIPGPDFPTAGIINGRAG-IIEAYRTGRGRI    
 8 O86092/1-506    99.8%  54.8%     LLINGSSGIAVGMATNIPPHNLNEVVDACLALLKNPETT----VDELIEIIPAPDFPTAGIIYGTMG-VKEAYRTGRGRV    
 9 GYRA_NEIGO/1-5 100.0%  51.4%     LLVNGSSGIAVGMATNIPPHNLTDTINACLRLLDEPKTE----IDELIDIIQAPDFPTGATIYGLGG-VREGYKTGRGRV    
10 Q47968/1-480    99.3%  54.6%     LLVNGSSGIAVGMSTNIPPHNLGEVVDAAVELIENPDAT----VADLMEHIKGPDFPTGANIVARNA-VHKAYKTGRGRV    
11 O24814/1-472   100.0%  53.7%     LLVNGATGIAVGMATNIPPHNLAETIDAVKLMMDNPEVT----TRELMEVLPGPDFPTGGLVMGKSG-IHRAYETGKGSI    
12 GYRA_BACS5/1-4  99.8%  58.4%     LLVNGASGIAVGMATNIPPHQLGEVIDGVLALSKNPDIS----VPELMEHIPGPDFPTGAEILGRSG-IRKAYQTGRGSI    
13 SARECF_3/1-473 100.0%  57.1%     LLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDIS----IAELMEDIEGPDFPTAGLILGKSG-IRRAYETGRGSI    
14 GYRA_CLOAB/1-4 100.0%  60.4%     LLVNGSAGIAVGMATNIPPHNLGEVIDGITMLIDNPEAT----ILELMAQIKGPDFPTAGIIMGKSG-IRAAYETGRGKI    
15 MG09251_4/1-47  99.8%  52.4%     LLANGSSGIAVGMSTSIPSHNLSELIAGLIMLIDNPQCT----FQELLTVIKGPDFPTGANIIYTKG-IESYFETGKGNV    
16 Q55738/1-477   100.0%  55.6%     LLINGSSGIAVGMATNIPPHNLGEVIDGAIALIRNPEIT----EQELMQIIPGPDFPTGAQILGRSG-IREAYLTGRGSI    
17 Q59784/1-498    99.8%  51.4%     MLVNGAGGIAVGMATNIPPHNLGEVVDATLAMIENPDIS----TERLMEIIPGPDFPTGGVILGRSG-ARKAYLEGRGSV    
18 GYRA_RICPR/1-4  99.8%  53.8%     LLVNGSGGIAVGMATNIPPHNLGEIIDACCLYIDNHDIE----ILDLLEVVKGPDFPTGSMILGISG-IRSAYLTGRGSI    
19 GYRA_MYCTU/1-4 100.0%  51.4%     LLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQG-TADAYKTGRGSI    
20 GYRA_STRCO/1-4  99.8%  53.2%     LLINGSAGIAVGMATNIPPHNLREVAAGAQWYLENYEASHEELLDALIERIKGPDFPTGALVVGRKG-IEEAYRTGRGSI    
21 GYRA_BORBU/1-4 100.0%  54.0%     LLVNGSSGIAVGMATNMAPHNLREICDAIVYMLDNENAS----IFDLLKIVKGPDFPTFGEIVYNDN-LIKAYKTGKGSV    
22 GYRA_TREPA/1-4 100.0%  49.9%     LLANGSSGIAVGMTTNMPPHNLREIAAAISAYIENPNLS----IQELCDCINGPDFPTGGIIFGKNG-IRQSYETGRGKI    
23 GYRA_SYNY3/1-4 100.0%  48.8%     LLLNGCSGIAVGMATSIPPHNLGEVVDGLIGLINKPDLS----DQELFKLIPGPDFPTGGHILDSEG-ILQAYQTGRGLI    
24 O67108/1-472    99.6%  54.4%     LLCNGTSGIAVGLATSIPPHNLTEVGNALVKLAQNPQIS----VDEIMEILKGPDFPTGGVIENFAQ-VKEIYKTGRGII    
25 O29785/1-466    98.9%  55.4%     LLINGSSGIAVGMATNMPPHNLAEVCEGIIAYIQNPEIS----VEELMKYVKGPDFPTGGVIVGVDG-IKEAYLTGRGKI    
26 O50510/1-474   100.0%  47.6%     LLVNGASGIAVGMATNMPPHNLREVIAAARHLIRYPNAD----LDALMKHVPGPDLPTGGRIVGLPG-IRDAYETGRGTF    
27 PARC_ECOLI/1-4  98.5%  43.2%     ILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTT----LDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSV    
28 PARC_HAEIN/1-4  98.5%  43.9%     ILLNGTTGIAVGMATDIPPHNINEIADAAVMLLDNPKAG----LDDVLEIVQGPDFPTEAEIISPKSEIRKIYEQGRGSI    
29 PARC_NEIGO/1-4  99.3%  41.0%     VLLNGASGIAVGMATEIPSHNLNEVTQAAIALLKKPTLE----TADLMQYIPAPDFAGGGQIITPADELRRIYETGKGSV    
30 PARC_CAUCR/1-4  99.1%  46.8%     LLANGSSGIAVGMATSIPPHNAAELIDACQLLLANPDAT----TADLLEKVPGPDFPTGGVIVESRASLLETYETGRGGV    
31 E1342381/1-471  99.1%  50.5%     LLANGSEGIAVGMATNIPPHNLHELCDALLYLIDNPQAG----INDIMNFIKGPDFPTGGIIIDKAEVINAAYTTGRGSF    
32 PARC_MYCGE/1-4  99.6%  41.3%     LFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCE----LKQILKIVKGPDFPTGGNVYFEKS-LSDIYQAGKGKF    
33 PARC_MYCPN/1-4 100.0%  41.5%     LFINGTSGIAAGYATNIAPHNVGELLDGLSYRIENPDCD----LKAILKIVKGPDFPTGGLVYFEQE-LANIYQTGKGKF    
34 G3513507/1-476 100.0%  41.5%     LLVNGAKGIAAGFATEIPPHNLGEVIDATIALIKNPTIS----IEELSEIVKGPDFPTGAIINGINE-IKKALSSGQGRI    
35 PARC_BACSU/1-4  99.8%  49.7%     LLVNGSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCS----VDELMELIKGPDFPTGGIIQGVDG-IRKAYETGKGKI    
36 PARC_STAAU/1-4  99.8%  46.2%     LLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDIT----VNQLMKYIKGPDFPTGGIIQGIDG-IKKAYESGKGRI    
37 PARC_STRPN/1-4  99.8%  45.3%     LLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAK----IDKLMEFLPGPDFPTGAIIQGRDE-IKKAYETGKGRV    
38 PARC_BORBU/1-4  93.8%  25.8%     ILIQGSEGIAVGMAAKILPHNFNEILNAVKSELLGESYD------------IYPDFPTGGIVDVNEY------ADGNGKV    
39 O84667/1-455    93.8%  24.8%     LLLHGVDGIAVGMTTKIFPHNFCDLLEAQIAILNDQPFS------------LLPDFPPGGTMDASDY------QDGLGSI    
40 TOP5_BPT4/1-44  94.9%  22.2%     VLLNGVSGIATGYATYILPHSVSSVKKAVLQALQGKKVT-----------KPKVEFPEFRGEVVEID----------GQY    
41 O24308/1-483    90.7%  15.3%     VLVNGSEGIGTGWSSYIPNYNPREIIANVRRLLNGEELV--------PMDPWYKGFRGTIEKSAKEGG-----------Y    
42 Q23670/1-511    95.1%  15.8%     VLVNGAQGIGTGWSTNIPNYNPRELVKNIKRLIAGEPQK--------ALAPWYKNFRGKIIQIDPSR------------F    
43 P90520/1-499    92.9%  14.1%     LLVNGSEGIGVGMSTSIPLFSPIDIIDQLMLRLNNQVALK-------KLIPWYRGFKGTISPDRHTYR------------    
44 TOP2_TRYCR/1-4  93.2%  15.4%     LLCNGSVGIGFGFASNIPPFHPLDVSAAVRSMINGEAAKV----VVRRLVPWAVGYQGEVRRGPEGE------------F    
45 O41065/1-434    91.2%  18.9%     ILVNGSSGIGTGSSTNIPSYNPKDIVDNVKRLISGEDLV--------EMKPWYKGFKGKIMETSPGV------------Y    
46 TOP2_ARATH/1-5  95.4%  16.4%     VLVNGAEGIGTGWSTFIPNYNPREIVANVRRLLNGESMV--------PMDPWYRGFKGTIEKTASKEGGCT--------Y    
47 TOP2_SCHPO/1-4  93.8%  16.8%     VLVNGAEGIGTGWSTFIPNYNPKDITANLRHMLNGEPLE--------IMTPWYRGFRGSITKVAPDR------------Y    
48 TOP2_PLAFK/1-4  95.1%  18.2%     ILVNGCEGIGTGYSSFIPNYNYKDIIDNIKRYINKEPLI--------PMVPWYKDFKGRIESNGKTG------------Y    
49 O59864/1-494    95.1%  17.0%     ILINGADGIGTGWSTSIPNYNPEDIVDNLKRMIRGEEIK--------PMQPWFKGFKGEVTQLGPDK------------Y    
50 TOP2_DROME/1-5  95.1%  15.3%     VLVNGAEGIGTGWSTKISNYNPREIMKNLRKMINGQEPS--------VMHPWYKNFLGRMEYVSDGR------------Y    
51 TOP2_CRIFA/1-4  93.2%  16.9%     LLCNGAVGIGFGFATNIPSFHPLDVSAAVRAMINGESAKQ----VVRNLVPWAVGFQGTVRRGPEKE------------Y    
52 D1034930/1-511  94.7%  15.4%     VLINGAEGIGTGWSTSIPPFNPLDVVNNIRHLLNDEEMD--------DMHPWFRGWTGTMEKIESQR------------Y    
53 TP2B_MOUSE/1-4  95.1%  17.1%     VLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLDPH--------PMLPNYKNFKGTIQELGQNQ------------Y    
54 TOP2_YEAST/1-5  94.7%  15.4%     ILVNGAEGIGTGWSTYIPPFNPLEIIKNIRHLMNDEELE--------QMHPWFRGWTGTIEEIEPLR------------Y    
55 TP2A_MOUSE/1-4  95.1%  17.3%     VLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPL--------PMLPSYKNFKGTIEELASNQ------------Y    
56 CER05D3_1/1-48  93.8%  16.1%     ILINGTEGIGTGWSTKIANRNPIDIIDMIRRKIDSISTEY-------EIPPFYEEFRGKLEVVTPTK------------F    
57 TOP2_CANAL/1-5  94.5%  14.8%     ILVNGAEGIGTGWSTNIPSYNPKDLVTNIRRLMNGEELQ--------EMTPWYKGWGGDLEPMGPQK------------F    
58 O16140/1-511    94.7%  16.7%     VLVNGVEGIGTGWSTKIPNYNPRDIAENLRRLLDGEKPK--------VMHPWYKNFKGNVEGFGD-K------------Y    
59 O61078/1-458    92.9%  14.1%     LLCNGRVGIGFGFPSKMPTFHPLEVSAAVRAMISGERAKQ----VVRLLVPWAVGLQGSIRRGPECE------------L    
   consensus/100%                   hhhpG..GIuhG.ss.h..hp..ph.t.........................h.th........................    
   consensus/90%                    lLhNGstGIusGhuo.lssap..-lhtshhhhhpt.th..............h.sa.sth.....tt............h    
   consensus/80%                    lLhNGupGIusGhuTpIPsas.t-lhsshhhhlps.php..........h..h.sF.ssh.h.s.tt............h    
   consensus/70%                    lLlNGusGIusGhuTsIPsaNhtEllsuhhthlps.php........h.h..hs-Fssss.hhsppt............h    

                     cov    pid 241          :         .         .         .         .         3         .         . 320
 1 GYRA_CAMJE/1-4 100.0% 100.0%     KVRAKTHIEKKTNK-------DVIVIDELPYQTNKARLIEQIAELVKER------------------QIEGISEVRDES-    
 2 GYRA_CAMFE/1-4 100.0%  79.0%     KLRAKTHIEKKPNK-------DVIVVDELPYQVNKAKLHADIADLVKEK------------------LIDGISEVRDES-    
 3 AE001496_3/1-4 100.0%  70.0%     KVRAKVHVEKTKNK-------EIIVLGEMPFQTNKAKLVEQISDLAREK------------------QIEGISEVRDES-    
 4 O84192/1-473   100.0%  53.8%     RLRARMHVEENSDKQR-----ENIILTEMPYNVNKSRLIEQIAELINEK------------------TLTGISDVRDES-    
 5 GYRA_ERWCA/1-5 100.0%  56.0%     YIRARAEVEADAKTGR-----ETIIVHEIPYQVNKARLIEKIAELVKDK------------------RIEGISALRDES-    
 6 GYRA_HAEIN/1-5  99.8%  53.1%     YVRARATVETNEKGRE------QIIVSELPYQVNKAKLVEKIAELIREK------------------KIEGISNITDLS-    
 7 GYRA_PSEAE/1-5 100.0%  55.5%     YIRARAVVEEMEKGGG----REQIIITELPYQLNKARLIEKIAELVKEK------------------KIEGISELRDES-    
 8 O86092/1-506    99.8%  54.8%     VMRGRTHVEDMEKGN-----RQALIIDELPYQVNKKSLIEKIAELVNEK------------------KIEGISDLRDES-    
 9 GYRA_NEIGO/1-5 100.0%  51.4%     VMRGKTHIEPIGKNGE----RERIVIDEIPYQVNKAKLVEKIGDLVREK------------------TLEGISELRDES-    
10 Q47968/1-480    99.3%  54.6%     RVRADYDVFEEEGR---------IVINELPYQENKARLIERIADDVNEG------------------KIEGIRDIRDES-    
11 O24814/1-472   100.0%  53.7%     VLRSRTEIETTKSG------RERIVVTEFPYMVNKTKVHEHIVRLAQEK------------------RIEGITAVRDES-    
12 GYRA_BACS5/1-4  99.8%  58.4%     TLRAKTEIEEHHG-------KQRIIVHEIPYQVNKAKLIEKIAELVRDK------------------KIDGITDLRDES-    
13 SARECF_3/1-473 100.0%  57.1%     QMRSRAVIEERGGG------RQRIVVTEIPFQVNKARMIEKIAELVRDK------------------KIDGITDLRDETS    
14 GYRA_CLOAB/1-4 100.0%  60.4%     TVRAKSEIEVEDNG------KQKIIITEIPYQVNKARLVESIADLVKDK------------------RIVGISDLRDES-    
15 MG09251_4/1-47  99.8%  52.4%     VIRSKVEIEQLQT-------RSALVVTEIPYMVNKTTLIEKIVELVKAE------------------EISGIADIRDES-    
16 Q55738/1-477   100.0%  55.6%     TMRGVASIETMEHPGRP--DRDAIIVTELPYQTNKAALIERIADLVNDK------------------KIDGIADIRDES-    
17 Q59784/1-498    99.8%  51.4%     IMRAKARVEEIRK------DRYAIVLDEIPYQVNKATMIEKIADMVREK------------------KIEGIAHVQDES-    
18 GYRA_RICPR/1-4  99.8%  53.8%     IMRGKAEIENVGN------SRQAIIITEIPYMVNKARLVEKIAEMVKEK------------------RIEGISDLRDES-    
19 GYRA_MYCTU/1-4 100.0%  51.4%     RMRGVVEVEEDSRG------RTSLVITELPYQVNHDNFITSIAEQVRDG------------------KLAGISNIEDQSS    
20 GYRA_STRCO/1-4  99.8%  53.2%     TMRAVVEVEEIQN-------RQCLVVTELPYQTNPDNLAQKIADLVKDG------------------KVGGIADVRDETS    
21 GYRA_BORBU/1-4 100.0%  54.0%     VIRARYHIEERAED------RNAIIVTEIPYTVNKSALLMKVALLAKEE------------------KLEGLLDIRDES-    
22 GYRA_TREPA/1-4 100.0%  49.9%     VVRARFTIETDSKG------RDTIIFTEVPYQVNTTMLVMRIGELARAK------------------VIEGIANVNDETS    
23 GYRA_SYNY3/1-4 100.0%  48.8%     PVRGVSHIETIRGEKKRSHNRTAIVITELPFQVNKAAWIEKIASLVNDG------------------KLDGISDLRDES-    
24 O67108/1-472    99.6%  54.4%     KVKGKAHVEKVQGGRER------IVITEIPYQVNKAELIKKIADNVRNG------------------KIKEISDIRDET-    
25 O29785/1-466    98.9%  55.4%     TVRGKVEVEKN-----------AIIIREVPYMVNKAKLVESIAELAKD-------------------RIDEIRTIRDES-    
26 O50510/1-474   100.0%  47.6%     KIRATVSVETVTAR------RKGLVVTELPFAVGPEKVISKIKDLVGAK------------------KIQGIADVKDLTD    
27 PARC_ECOLI/1-4  98.5%  43.2%     RMRAVWKKEDGA-----------VVISALPHQVSGARVLEQIAAQMRNK------------------KLPMVDDLRDESD    
28 PARC_HAEIN/1-4  98.5%  43.9%     KMRATWKKEDGE-----------IIISALPHQSSPSKVIAQIAEQMTAK------------------KLPMLEDIRDEAD    
29 PARC_NEIGO/1-4  99.3%  41.0%     RVRARYEIEKLARG------QWRVIVTELPPNANSAKILAEIEEQTNPKPKAGKKQLNQDRLNTKKLMLDLIDRVRDESD    
30 PARC_CAUCR/1-4  99.1%  46.8%     RMRAKWEKEDTGRG------TYQIVVTEIPYQVKKSDLVEQLADLIDSK------------------KAALLGDVRDES-    
31 E1342381/1-471  99.1%  50.5%     RVRSRWEKEELSYG------TYQIVVTEIPYQIQKSKLIEQIAILLKDK------------------KIPLISSIRDES-    
32 PARC_MYCGE/1-4  99.6%  41.3%     IIQAKYEVNKNL---------NQIEITQIPYETLKANIVKQIEEIIFDN------------------KLSAIESVIDSS-    
33 PARC_MYCPN/1-4 100.0%  41.5%     VIQAKYETNTAFGQ-------NQIVITEIPYETVKANIVKQIEELISDN------------------KLSALESVIDSS-    
34 G3513507/1-476 100.0%  41.5%     TISSKYHYVYDKKDESK---IIGIEIIEIPFGVVKSKLVADIDAIAIDK------------------KISGIKEVLDQT-    
35 PARC_BACSU/1-4  99.8%  49.7%     IIRGKAEIETIRGGRE------QIVITEIPFEVNKANLVKKMDEFRIDK------------------KVEGISEVRDET-    
36 PARC_STAAU/1-4  99.8%  46.2%     IVRSKVEEETLRNGRK------QLIITEIPYEVNKSSLVKRIDELRADK------------------KVDGIVEVRDET-    
37 PARC_STRPN/1-4  99.8%  45.3%     VVRSKTEIEKLKGGKE------QIVITEIPYEINKANLVKKIDDVRVNN------------------KVAGIAEVRDES-    
38 PARC_BORBU/1-4  93.8%  25.8%     LVRAKIETIDEKT----------IVIRELPFGETTESLISSIEKAIRKN-------------------YIKVSSINDFT-    
39 O84667/1-455    93.8%  24.8%     VLRATIDIINDKT----------LLIKEICPSTTTETLIRSIENAAKRG-------------------IIKIDSIQDFS-    
40 TOP5_BPT4/1-44  94.9%  22.2%     EIRGTYKFTSRTQ----------MHITEIPYKYDRETYVSKILDPLENK------------------GFITWDDACGEHG    
41 O24308/1-483    90.7%  15.3%     IVNGTVTEIDE----------QTFRITELPIRKWTQDYKQFLESITDGAPN----------------VKDPLIEDFRQNG    
42 Q23670/1-511    95.1%  15.8%     ACYGEVAVLDD----------NTIEITELPIKQWTQDYKEKVLEGLMESSD----------------KKSPVIVDYKEYH    
43 P90520/1-499    92.9%  14.1%     -TNGVIKLVG-----------RNLEITELPIGRWTSDYKEVLNDLIDKD----------------------VIKSFQESN    
44 TOP2_TRYCR/1-4  93.2%  15.4%     IAAGSYQYYVD----------GRVHVTEIPWTLSIEAFRDHISVLASKD----------------------VVQRIADYS    
45 O41065/1-434    91.2%  18.9%     VTKGLYMPNG-----------KTIVVSELPVGKWTHDYKEHLDGLLE----------------------KKIISYFREKH    
46 TOP2_ARATH/1-5  95.4%  16.4%     TITGLYEEVDE----------TTIRITELPIRRWNDDYKNFLQSLKTDNG-------------------APFFQDVKAYN    
47 TOP2_SCHPO/1-4  93.8%  16.8%     KISGIINQIGE----------NKVEITELPIRFWTQDMKEYLEAGLVGTEK-----------------IRKFIVDYESHH    
48 TOP2_PLAFK/1-4  95.1%  18.2%     ETIGIINKIDN----------DTLEITELPIKKWTQDYKEFLEELLTD-------------------EKHQLILDYIDNS    
49 O59864/1-494    95.1%  17.0%     KFSGLIKQVSD----------KELEVTELPIRTWTQDFINKLEEMIKAD------------------KAPSLIKDYKDYN    
50 TOP2_DROME/1-5  95.1%  15.3%     IQTGNIQILSG----------NRLEISELPVGVWTQNYKENVLEPLSNGTE----------------KVKGIISEYREYH    
51 TOP2_CRIFA/1-4  93.2%  16.9%     IAVGKYTAHRN----------GRLHVSELPWMTSIEAFRSHISSLASSD----------------------VVQRIADYS    
52 D1034930/1-511  94.7%  15.4%     RMYGRIEQVGP----------NTLEITELPARTWTSTIKEHLLLGLGGSEK----------------V-KPWIKDMEEQH    
53 TP2B_MOUSE/1-4  95.1%  17.1%     AVSGEIFVVDR----------NTVEITELPVRTWTQVYKEQVLEPMLNGTD----------------KTPALISDYKEYH    
54 TOP2_YEAST/1-5  94.7%  15.4%     RMYGRIEQIGD----------NVLEITELPARTWTSTIKEYLLLGLSGNDK----------------I-KPWIKDMEEQH    
55 TP2A_MOUSE/1-4  95.1%  17.3%     VINGEVAILDS----------TTIEISELPIRTWTQTYKEQVLEPMLNGTE----------------KTPSLITDYREYH    
56 CER05D3_1/1-48  93.8%  16.1%     ISSGKIQLIRPERKNAST---FSIEIVELPIGIWTSKYKEKLSKIVETLP----------------------VLEFSERH    
57 TOP2_CANAL/1-5  94.5%  14.8%     KVSGRIEQIDS----------NTVEITEIPVKTWTNNVKEFLLSGFG-NEK----------------T-QPWIKDMEEHH    
58 O16140/1-511    94.7%  16.7%     VISGEAAILPG----------DKIEITELPVGTWTHNYKENVLEPML-GTD----------------KVKPLISEYREYN    
59 O61078/1-458    92.9%  14.1%     IAVGKYTTARA----------GRMHVTELPWMTSIEAFRTHISSLAAIDR---------------------LVKRIADYS    
   consensus/100%                   ...u...................h.h.ths.....t.hh..h...h..................................    
   consensus/90%                    hh.u.ht..t.............l.lpElPh.h.htthht.l.t.h.tt......................h.t.hpp..    
   consensus/80%                    hhpuphph.p............tl.lsElPhth.ptphhppltphhttt...................h..l.p.hc-p.    
   consensus/70%                    hhpuphph.p............tlhloElPhps.ptphhcpltchhppp..................phtsl.phh-Es.    

                     cov    pid 321          .         .         :         .         .         .         .         4 400
 1 GYRA_CAMJE/1-4 100.0% 100.0%     NKEGIRVVIELKRE---AMSEIVLNNLFKSTTMESTFGVIMLAIH--NKEPKIFSLLE--LLNLFLTHRKTVIIRRTIFE    
 2 GYRA_CAMFE/1-4 100.0%  79.0%     DRDGIRLVIELKRD---AMSEIVLNNLFKSTQMEVTFGVIMLAIN--NKEPKVFSLLE--LLKLFLNHRKTVIIRRTIFE    
 3 AE001496_3/1-4 100.0%  70.0%     DREGIRVVIELKRD---AMSEIVLNHLYKLTTMETTFSIILLAIY--NKEPKIFTLLE--LLRLFLNHRKTIIIRRTIFE    
 4 O84192/1-473   100.0%  53.8%     DKDGIRVVLELKKG---ESSEVVINRLYKFTDVQVTFGANMLALD--KNLPRTMNIHR--MISAWIRHRMDVIQRRTRYE    
 5 GYRA_ERWCA/1-5 100.0%  56.0%     DKDGMRIVIEIKRD---AVGEVVLNNLYSQTQLQTSFGINMVALH--QGQPKIMPLKD--ILVAFVRHRREVVTRRTIFE    
 6 GYRA_HAEIN/1-5  99.8%  53.1%     NKEGIRIEIDIKRD---AVGEVVLNHLYSLTQMQVTFGINMVALD--HGQPRLFNLKE--IIEAFVLHRREVVTRRSIFE    
 7 GYRA_PSEAE/1-5 100.0%  55.5%     DKDGMRVVIELRRG---EVGEVVLNNLYAQTQLQSVFGINVVALV--DGQPRTLNLKD--MLEVFVRHRREVVTRRTVYE    
 8 O86092/1-506    99.8%  54.8%     DKSGMRVVIELKRG---EVPEVILNNLYKQTQLQDTFGMNMVALL--DGQPRLLNLKQ--MLEAFFGHRREVITRRTVFE    
 9 GYRA_NEIGO/1-5 100.0%  51.4%     DKSGMRVVIELKRN---ENAEVVLNQLYKLTPLQDSFGINMVVLV--DGQPRLLNLKQ--ILSEFLRHRREVVTRRTLFR    
10 Q47968/1-480    99.3%  54.6%     ERDGIRVVIELKRG---AMAEVVKNQLLDN-HLESTFGVINLALV--DGQPQVLTLKE--TLEHYLDHRRDVVRRRSEYE    
11 O24814/1-472   100.0%  53.7%     SREGVRFVIEVRRD---ASANVILNNLFKLTQLQTNFSFNMLAIE--KGVPKILSLRQ--ILADYIAHQKEVVVRRTQFD    
12 GYRA_BACS5/1-4  99.8%  58.4%     DRNGMRIVIEVRKD---ANANVLLNNLYKQTALQTSFGINLLALV--EGQPKVLNLKE--CLEHYLAHQVIVIRRRTAFE    
13 SARECF_3/1-473 100.0%  57.1%     LRTGVRVVIDVRKD---ANASVILNNLYKQTPLQTSFGVNMIALV--NGRPKLINLKE--ALVHYLEHQKTVVRRRTQYN    
14 GYRA_CLOAB/1-4 100.0%  60.4%     DRDGMRIVIEIKKD---ANSNIILNQLYKHTRLQDTFGINMLALV--DNRPEVLNLKQ--ILQHYIKFQEQVIRRRTEFD    
15 MG09251_4/1-47  99.8%  52.4%     SREGIRLVIEVKRD---TVPEVLLNQLFKSTRLQVRFPVNMLALV--KGAPVLLNMKQ--ALEVYLDHQIDVLVRKTKFV    
16 Q55738/1-477   100.0%  55.6%     DRDGMRIVIELKRD---AYARVVLNNLYKQTPIQSNFGANLLALV--NGTPEVLTIKK--FLTVFWEFRIETITRRTRYE    
17 Q59784/1-498    99.8%  51.4%     DRVGVRVVIELKRD---ATPEVVLNQLWRFTPMQTTFGCNMLALN--GGRPEQLTLRD--FLSHFLTFREDVVARRTAYE    
18 GYRA_RICPR/1-4  99.8%  53.8%     NKNGIRIFIELKKD---VVAEVVLNQIYACTQLQTNFGVIMLALK--DGLPKVMNLKE--VIAAFVSFREVVITNRTIYL    
19 GYRA_MYCTU/1-4 100.0%  51.4%     DRVGLRIVIEIKRD---AVAKVVINNLYKHTQLQTSFGANMLAIV--DGVPRTLRLDQ--LIRYYVDHQLDVIVRRTTYR    
20 GYRA_STRCO/1-4  99.8%  53.2%     SRTGQRLVIVLKRD---AVAKVVLNNLYKHTDLQSNFGANMLALV--DGVPRTLSLDA--FIRHWVNHQIEVIVRRTRFR    
21 GYRA_BORBU/1-4 100.0%  54.0%     DREGIRIVLEVKRG---FDPHVIMNLLYEYTEFKKHFSINNLALV--NGIPKQLNLEE--LLFEFIEHRKNIIERRIEFD    
22 GYRA_TREPA/1-4 100.0%  49.9%     DRTGLRIVVELKKG---TPAQVVLNHLFAKTPLQSSFNVINLALV--EGRPRMLTLKD--LVRYFVEHRVDVVTRRAHFE    
23 GYRA_SYNY3/1-4 100.0%  48.8%     DRTGMRVVIELKRD---AEPNAILQKLYRMTPLQSNFGVIFLALV--NNQPVQMSLRQ--ILQEFLQFREDTLLRQYENE    
24 O67108/1-472    99.6%  54.4%     DKEGIRIVVELKRD---AKGEEVLKKLYKYTPLEKGFPVNLVVLI--DKEPKLVDIKT--LLREFIKHRLEVILRRSKYF    
25 O29785/1-466    98.9%  55.4%     DREGIRVVIELKSG---SNPETVIKKLYAYSNLQTTFGIINLALV--DNEPRILNLKE--LIALFVDHRREIIRRRTTYD    
26 O50510/1-474   100.0%  47.6%     RAHGLRLVIEIKNG---FVPEAVLEQLYKLTAMEESFGINNVALV--DGQPLTLGLKE--LLEVYLDHRFTVVRRRSEFR    
27 PARC_ECOLI/1-4  98.5%  43.2%     HENPTRLVIVPRSNR--VDMDQVMNHLFATTDLEKSYRINLNMIGL-DGRPAVKNLLE--ILSEWLVFRRDTVRRRLNYR    
28 PARC_HAEIN/1-4  98.5%  43.9%     HENPIRIVLVPRSNR--VDTDALMAHLFATTDLEKSYRVNMNMIGL-DHKPAVKGLLE--ILNEWLDFRRTTVTRRLQYR    
29 PARC_NEIGO/1-4  99.3%  41.0%     GEHPVRLVFEPKSSR--IDTDTFINTLMAQTSLEGNVSMNLVMMGL-DNRPAQKNLKT--ILQEWLDFRIVTVTRRLKFR    
30 PARC_CAUCR/1-4  99.1%  46.8%     -AEDIRLVLEPKSKN--VEPEVLMESLFKLSALESRFPVNINVLDA-RGTPGVMGIKQ--ALMAFLAHRREVLTRRARHR    
31 E1342381/1-471  99.1%  50.5%     -TDIIRVVIEPRDRS--CDPQIVMESLFKLTNLESRIQLNMNVIGS-NNVPRVMNILE--ILQEFLVHRKNIIIRRSTYL    
32 PARC_MYCGE/1-4  99.6%  41.3%     DRNGIRIIIKHKDF---LPAEKIMAFLFKHTQLQVNFNLNNTVIA--NRFPIQIGLLS--YLDHFLKFCHELIINKAKYE    
33 PARC_MYCPN/1-4 100.0%  41.5%     DRSGIRIIINHKDF---LSADKIMAFLFKHTQLQVNFNLNNTVIA--NRCPVRVGLLA--YFDQFLAFAHELIINSAKYD    
34 G3513507/1-476 100.0%  41.5%     DRNGISIFIQLEDG---ANADAIIAYLMNKTELSISYSYNMVAID--NNRPVILNLYS--ALIAYLSHLKEVNINGINYD    
35 PARC_BACSU/1-4  99.8%  49.7%     DRTGLRVVIELKKE---ADAKGILNFLYKNTDLQITYNFNMVAIH--NRRPMLMSLPS--ILDAYIGHQKEVVTNRSVYE    
36 PARC_STAAU/1-4  99.8%  46.2%     DRTGLRIAIELKKD---VNSESIKNYLYKNSDLQISYNFNMVAIS--DGRPKLMGIRQ--IIDSYLNHQIEVVANRTKFE    
37 PARC_STRPN/1-4  99.8%  45.3%     DRDGLRIAIELKKD---ANTELVLNYLFKYTDLQINYNFNMVAID--NFTPRQVGIVP--ILSSYIAHRREVILARSRFD    
38 PARC_BORBU/1-4  93.8%  25.8%     -AENVAIELSLPRG---VYASEVIEKLYHYTNCQISISVNLLLLS--ERYPVVYTIKD--LIKFHAAHLQKILKMELELQ    
39 O84667/1-455    93.8%  24.8%     -TDLPHIEIKLPKG---IYAKDLLRPLYTHTECQVILTSRPTAIY--QGKPWETTISE--ILRLQTKTLQNYLKKELLIL    
40 TOP5_BPT4/1-44  94.9%  22.2%     FGFKVKFRKEYSLS---DNEEERHAKIMKDFGLIERRSQNITVINEKGKLQVYDNVVD--LIKDFVEVRKTYVQKRIDNK    
41 O24308/1-483    90.7%  15.3%     DDAIVDIEIKMKPE---KIATILQEGLFKKFKLTSTISTSNMHLFDAE-GNKKFDTPE-QILEEFFPLRLDYYEKSKEYI    
42 Q23670/1-511    95.1%  15.8%     TDTTVKFVVKLSPG--KLRELERGQDLHQVFKLQAVINTTCMVLFDAAGCLRTYTSPE-AITQEFYDSRQEKYVQRKEYL    
43 P90520/1-499    92.9%  14.1%     TENSVHFTILLNNNQLEQMEDLTENELIKLFKLSASLNFHLTCFDENS--KIQKLESVEEIIDQFYKVRLQFYGKRREYL    
44 TOP2_TRYCR/1-4  93.2%  15.4%     GANHVDIDLELTNG-----AMTTYAECESELSLTQRIYIN-GTVFSPTGVLTPLEGDLAPVLQWHYDRRLDLYKKRRQRN    
45 O41065/1-434    91.2%  18.9%     SDTDVLFEIDFVGN-----------PNIDILKLETTIRSTNMHAFDPSGKIKKYDTPL-DIIRDWFEVRKDLYVKRKAYL    
46 TOP2_ARATH/1-5  95.4%  16.4%     DEKSVDFDLILSEE---NMLAARQEGFLKKFKLTTTIATSNMHLFDKKGVIKKYVTPE-QILEEFFDLRFEYYEKRKETV    
47 TOP2_SCHPO/1-4  93.8%  16.8%     GEGIVHFNVTLTEA---GMKEALNESLEVKFKLSRTQATSNMIAFDASGRIKKYDSVE-DILTEFYEVRLRTYQRRKEHM    
48 TOP2_PLAFK/1-4  95.1%  18.2%     SHEDICFTIKMDPA---KLQKAEEEGLEKVFKLKSTLTTTNMTLFDPNLKLQRYSTEL-DILKEFCYQRLKAYENRKSYL    
49 O59864/1-494    95.1%  17.0%     TNSDVHLVLQLDEK--NVKEPLTQEFLEEKFKLSKTIATTNLVAFNAEGQMTKYPNVE-AILEEFYRLRLKFYGKRKQHQ    
50 TOP2_DROME/1-5  95.1%  15.3%     TDTTVRFVISFAPG-EFERIHAEEGGFYRVFKLTTTLSTNQMHAFDQNNCLRRFPTAI-DILKEYYKLRREYYARRRDFL    
51 TOP2_CRIFA/1-4  93.2%  16.9%     GANHIDIDLIVREG-----SMTTWAECETDLALSQRIYIN-GTVFSPDGTLSPIDADLSPVLQWHYDRRLDLYKRRRTRQ    
52 D1034930/1-511  94.7%  15.4%     AET-IKFIIKLTDE---EMTKTRKLGFYERFKLISPISLQNMVAFDYRGKIKKYDHVH-EILKDFYEVRLEYYQKRKDYM    
53 TP2B_MOUSE/1-4  95.1%  17.1%     TDTTVKFVVKMTEE---KLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQ-DILKEFFDLRLSYYGLRKEWL    
54 TOP2_YEAST/1-5  94.7%  15.4%     DDN-IKFIITLSPE---EMAKTRKIGFYERFKLISPISLMNMVAFDPHGKIKKYNSVN-EILSEFYYVRLEYYQKRKDHM    
55 TP2A_MOUSE/1-4  95.1%  17.3%     TDTTVKFVIKMTEE---KLAEAERVGLHKVFKLQSSLTCNSMVLFDHVGCLKKYDTVL-DILRDFFELRLKYYGLRKEWL    
56 CER05D3_1/1-48  93.8%  16.1%     TEKRVHFRITLDRKKSSRFLQKSNSDLLNYFKLRTSLTEN-RVLFDRNGELKEFGNIS-EIAAEFFEVRRDLYEKRLKIQ    
57 TOP2_CANAL/1-5  94.5%  14.8%     TTS-IRFVVKLTDA---EMQKSLRIGLLERFKLVSSLSLANMVAFDPMGRIKKYNDVL-EIIKDFYYVRLEYYQKRKDYM    
58 O16140/1-511    94.7%  16.7%     TDTTVRFVVSLLPG---KLSEIEAEGIHKVFKLQTTISMTCMNAFDYNCCLEKYDKVE-EILREFYDLRVKYYVRRKDYL    
59 O61078/1-458    92.9%  14.1%     GANQIDIEMIVSEG-----SMRTWAECETDLGLRHRIYIN-GTVFSPDGTLIPIDGDLTPVLQWHYDRRLNLYKRR-RRQ    
   consensus/100%                   .t....h.h.......................h..........h................hh...h.....h...t....    
   consensus/90%                    .tp.hch.l.hp.t..........t.h.t.h.hp.th.h..hhh...tt....hs.....hlt.ah.hp.phh.pc..h.    
   consensus/80%                    scptl+hhlphppt......phhhttLhp.htLp.shshp.hsl...pt..h.hsh.t..hlp.ahthphphhhpRtta.    
   consensus/70%                    scssl+lslclccs...h.sphhhptLachhpLpsshshs.hslh..ssp.phhshhp..lLptahphRhchht+Rppa.    

                     cov    pid 401          .         .         .         .         :         .         .         . 480
 1 GYRA_CAMJE/1-4 100.0% 100.0%     LQKAR--ARAHILEGLKIALDNIDEVIALIKNSSDNN-TARDSLVAK---------------------------------    
 2 GYRA_CAMFE/1-4 100.0%  79.0%     LQKAR--ARAHILEGLKIALDNIDAVINLIKTSADTN-SARDGLMAK---------------------------------    
 3 AE001496_3/1-4 100.0%  70.0%     LEKAK--ARAHILEGYLIALDNIDEIVRLIKTSPSPE-AAKNALIER---------------------------------    
 4 O84192/1-473   100.0%  53.8%     LNKAE--ARAHILEGFLKALSCMDEVVKTIRESSNKE-HAKQQLVEL---------------------------------    
 5 GYRA_ERWCA/1-5 100.0%  56.0%     LRKAR--DRAHILEGLAIALANIDPIIELIRRAASPA-EAKASLIAQAWELGSVATMLERAGDDAARPEWLEPEFGIRDG    
 6 GYRA_HAEIN/1-5  99.8%  53.1%     LRKAR--ERTHILEGLAVARSNIDEMIAIIRNSKNRE-EAATSISSRSWTLHSDIINLLDASARPDELEENLGIQGEQ--    
 7 GYRA_PSEAE/1-5 100.0%  55.5%     LRKAR--ERGHILEGQAVALSNIDPVIELIKSSPTPA-EAKERLIATAWESSAVEAMVERAGADACRPEDLDPQYGLRDG    
 8 O86092/1-506    99.8%  54.8%     LGKA---ERGHVLEGLAVALANVDEMIALIKAAPTPP-EAKKSLMSRTWTSPVVEEMLKRAAMEASRPEGLSVDFGMTPN    
 9 GYRA_NEIGO/1-5 100.0%  51.4%     LKKAR--HEGHIAERKAVALSNIDEIIKLIKESPNAA-EAKEKLLARPWASSLVEEMLTRSGLDLEMMRPEGLVANIGLK    
10 Q47968/1-480    99.3%  54.6%     LAEAE--DRAHILDGRLKALDNIDDVVETIRNSESRD-DAKAALRGEVEVEVDGEPLPT---------------------    
11 O24814/1-472   100.0%  53.7%     KDKAE--ARAHILEGLLIALDHLDEVITIIRNSQTDA-EAQAELMAR---------------------------------    
12 GYRA_BACS5/1-4  99.8%  58.4%     LRKAE--ARAHILEGLRIALDHLDEVISLIRSSQTTE-IARNGLMER---------------------------------    
13 SARECF_3/1-473 100.0%  57.1%     LRKAK--DRAHILEGLRIALDHIDEIISTIRESDTDK-VAMESLQQR---------------------------------    
14 GYRA_CLOAB/1-4 100.0%  60.4%     LEKAS--ARAHILEGLKIALDHIDEVISLIRGSKTAQ-EAKLGLMDK---------------------------------    
15 MG09251_4/1-47  99.8%  52.4%     LNKQQ--ERYHILSGLLIAALNIDEVVAIIKKSANNQ-EAINTLNTK---------------------------------    
16 Q55738/1-477   100.0%  55.6%     LRKAE--ERDHLLQGLLIALDNLDAVIRLIRGAADTA-SAKTELVEG---------------------------------    
17 Q59784/1-498    99.8%  51.4%     LRKAR--ERSHILCGLAVAVSNVDEVVATIRSLADPA-QARERLMTRRLPSADIADYIRLIDDPSHTINEDGT-------    
18 GYRA_RICPR/1-4  99.8%  53.8%     LNKAR--DRAHILLGLTIAISNIDEIIYIIKASNDTN-LAKQELMARQWEVLDILPLIKLVDDKVILNERGT--------    
19 GYRA_MYCTU/1-4 100.0%  51.4%     LRKAN--ERAHILRGLVKALDALDEVIALIRASETVD-IARAGLIEL---------------------------------    
20 GYRA_STRCO/1-4  99.8%  53.2%     LRKAE--ERAHILRGLLKALDAIDEVIALIRRSDTVE-IARGGLMDL---------------------------------    
21 GYRA_BORBU/1-4 100.0%  54.0%     LRKAK--EKAHVLEGLNIALNNIDEVIKIIKSSKLAK-DARERLVSN---------------------------------    
22 GYRA_TREPA/1-4 100.0%  49.9%     LRKAQ--ERIHLVRALIRALDAIDKIITLIRHSQNTE-LAKQRLREQ---------------------------------    
23 GYRA_SYNY3/1-4 100.0%  48.8%     LGENR--RRLELLTGLLIGLENLDALIEILRFAADGT-TAKIQLQER---------------------------------    
24 O67108/1-472    99.6%  54.4%     LKKVQ--DRLHIVEGLLKAINFIDDIIERIRRSKDAS-EARNYLMEE---------------------------------    
25 O29785/1-466    98.9%  55.4%     LEKAQ--ERLHIVEGLKVVVEDIDNAINLIKSSSSPS-EAKGKLIET---------------------------------    
26 O50510/1-474   100.0%  47.6%     RSKRR--DRLHLVEGLLTALVDIDEVIRLIRSSENSA-QAKQRLMER---------------------------------    
27 PARC_ECOLI/1-4  98.5%  43.2%     LEKVL--KRLHILEGLLVAFLNIDEVIEIIRNEDEP----KPALMSR---------------------------------    
28 PARC_HAEIN/1-4  98.5%  43.9%     LDKVL--SRLHILEGLMIAFLNIDEVIEIIRHEDDP----KAELMAR---------------------------------    
29 PARC_NEIGO/1-4  99.3%  41.0%     LNQVE--KRLHILEGRLKVFLHIDEVIKVIRESDDP----KADLMAV---------------------------------    
30 PARC_CAUCR/1-4  99.1%  46.8%     LAKIE--ARLHILDGLLIAYLNLDEVIRIVRYEDKP----KEKLIET---------------------------------    
31 E1342381/1-471  99.1%  50.5%     LNKIK--QRLEILKVLRIVYLNLDEIIEIIREEDEP----KTIIMER---------------------------------    
32 PARC_MYCGE/1-4  99.6%  41.3%     LELAS--KRLEIILGLIKAISIIDKIIKLIRSAVDKS-DAREKLIDN---------------------------------    
33 PARC_MYCPN/1-4 100.0%  41.5%     LALAN--KRLEIIKGLIKAVSMIDEIIRLIRRATDKQ-DAKTKLIDK---------------------------------    
34 G3513507/1-476 100.0%  41.5%     LKKFK--LRLEIVEGFIKVAEISDEVIHLIKESDNSKKGVILALMNK---------------------------------    
35 PARC_BACSU/1-4  99.8%  49.7%     LQKAK--DRHHIVEGLMKALSILDEVIATIRSSSDKR-DAKNNLIAK---------------------------------    
36 PARC_STAAU/1-4  99.8%  46.2%     LDNAE--KRMHIVEGLIKALSILDKVIELIRSSKNKR-DAKENLIEV---------------------------------    
37 PARC_STRPN/1-4  99.8%  45.3%     KEKAE--KRLHIVEGLIRVISILDEVIALIRASENKA-DAKENLKVS---------------------------------    
38 PARC_BORBU/1-4  93.8%  25.8%     KSKILE-KIFYKTLEQIFIEKKIYKLLETISKEENILSIILSEVLRHKESFS----------------------------    
39 O84667/1-455    93.8%  24.8%     EDSLSR-ELYHKTLEYLFIKHKLYDTVRSMLSKRKTSPSSSTIHNAVLEALTPFLDTL----------------------    
40 TOP5_BPT4/1-44  94.9%  22.2%     IKETESAFRLAFAKAHFIKKVISGEIVVQGKTRKELTEELSKIDMYS---------------------------------    
41 O24308/1-483    90.7%  15.3%     LGNLNRLLLILDNKVRFILGVVNGEIIVSNRKKAELLIELKEKGFTPMPRKGKSTKPQVAGANDDDSEEQEDAEPETASQ    
42 Q23670/1-511    95.1%  15.8%     LGVLQAQSKRLTNQARFILAKINNEIVLENKKKAAIVDVLIKMKFDADPVKKWKEEQKLKELRESGEIELDEDDLAAVAV    
43 P90520/1-499    92.9%  14.1%     LKSLDNQIKRLTTTIQFLEVIASGKLKIQGRSKQDLIKELESGEIVGFENFGTHPPEVYQHLFSLSILDITKERIDNLTN    
44 TOP2_TRYCR/1-4  93.2%  15.4%     LGLLEAELAREKSTLKFVTHFREGKIDIVNATDDSLAKTCSKLGMVRVD-------------------------------    
45 O41065/1-434    91.2%  18.9%     LEDLTHRTNIAQNKHRFITMVNNDEIIINKKHESVISAELEKLNFYKVD-------------------------------    
46 TOP2_ARATH/1-5  95.4%  16.4%     VKNMEIELLKLENKARFILAVLSGEIIVNKRKKADIVEDLRQKGFTPFPRKAESVEAAIAGAVDDDAAEEPEEILVDPES    
47 TOP2_SCHPO/1-4  93.8%  16.8%     VNELEKRFDRFSNQARFIHMIIEGELVVSKKKKKDLIVELKEKKFQPISKPKKGHLVDLEVENALAEEEQSGDVSQDEDS    
48 TOP2_PLAFK/1-4  95.1%  18.2%     ISKLEKEKRIISNKTKFILAIVNNELIVNKKKKKVLVEELYRKGYDPYKDINKIKKEEIFEQELLDAADNPEDNEE----    
49 O59864/1-494    95.1%  17.0%     LDQLQIELEKLTNQARFVHMIIDGDLVVSKKKKSVLVKELDSLGFKRFNKTADAAKAGETEKVIEASEDEDTEAQ-----    
50 TOP2_DROME/1-5  95.1%  15.3%     VGQLTAQADRLSDQARFILEKCEKKLVVENKQRKAMCDELLKRGYRPDPVKEWQRRIKMEDAEQADEEDEEEEEAAPSVS    
51 TOP2_CRIFA/1-4  93.2%  16.9%     IGLLEMDLARLQSTRKFVEHFRQGHIDFLAATDDTLTKTCVKLGLVRVD-------------------------------    
52 D1034930/1-511  94.7%  15.4%     TGRLQWEAEKLSFQVKFIKMIIDKSLIVTNKPKKQLISELEELGFPRINKEGKPHFGKIDEEVEAIISEDEDEDLEESEE    
53 TP2B_MOUSE/1-4  95.1%  17.1%     VGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEDSQNQHDDSS------    
54 TOP2_YEAST/1-5  94.7%  15.4%     SERLQWEVEKYSFQVKFIKMIIEKELTVTNKPRNAIIQELENLGFPRFNKEGKPYYGSPNDEIAEQINDVKGATSDEEDE    
55 TP2A_MOUSE/1-4  95.1%  17.3%     LGMLGAESSKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRGYDSDPVKAWKEAQQKVPDEEENEESDTETS------    
56 CER05D3_1/1-48  93.8%  16.1%     KEECEAKLIYVENQLNFIEMVTNGTIEIRSMGRNQLEEKLQEMGFRVDPMATIAKNSKKVNLINYEDFQY----------    
57 TOP2_CANAL/1-5  94.5%  14.8%     TDNLQNQLLMLSEQARFIKMIIEKQLSVANKKKKQLVALLEEHNFTKFSKDGKPIKSSEELLTGDDADEEEETQEQEGDE    
58 O16140/1-511    94.7%  16.7%     EGQLQAEADKLSNQARFILKKCDKGLVIENKKRKAMVEELIKRGYAPDPIADWKKRASKIQGLTALEDDDAQESEEEEPE    
59 O61078/1-458    92.9%  14.1%     IRLDEIDLARRQSTRKFVKHFGLGHIDLIRATDETLIKACVKMGLVRVD-------------------------------    
   consensus/100%                   .t...............h.......h......................................................    
   consensus/90%                    ht.ht....h...phhhhhh...ttlh...ptttt......t.hh...................................    
   consensus/80%                    ltphp...phh..pshhhhh...scll..h+tpts....hht.hht..................................    
   consensus/70%                    lpphp..tchthhpuhhlth...ccllhhh+pppsh..thppthhtp.................................    

                     cov    pid 481          .         5         .         .         .         .         :   ] 554
 1 GYRA_CAMJE/1-4 100.0% 100.0%     ---------------------FGLSELQANAILDMKLGRLTGLE-REKIENELAELMKEIARLEEILKSETLLE    
 2 GYRA_CAMFE/1-4 100.0%  79.0%     ---------------------FGLSELQSNAILDMRLSKLTGLE-REKLEAELKEILELIEKLDAILKSETLIE    
 3 AE001496_3/1-4 100.0%  70.0%     ---------------------FSLSEIQSKAILEMRLQRLTGLE-RDKIKEEYQNLLELIDDLNGILKSEDRLN    
 4 O84192/1-473   100.0%  53.8%     ---------------------FSFSEAQALAILELRLYQLTGLE-ADKVQKEYSELLEKITYYRKVLAEEELVK    
 5 GYRA_ERWCA/1-5 100.0%  56.0%     R--------------------YYLTEQQAQAILDLRLQKLTGME-HEKLLDEYKELLAEIAELLYILNSPERLM    
 6 GYRA_HAEIN/1-5  99.8%  53.1%     ---------------------YYLSPAQVNAILELRLHRLTGIA-FEEVIKEYEELLVKIADLLHILSSAERLM    
 7 GYRA_PSEAE/1-5 100.0%  55.5%     K--------------------YYLSPEQAQAILELRLHRLTGLE-HEKLLSEYQEILNLIGELIRILTNPARLM    
 8 O86092/1-506    99.8%  54.8%     G--------------------YRLSDVQAQEILQMRLQRLTGLE-QDKIVNEYKEVMDVIADLLDILAKPERVT    
 9 GYRA_NEIGO/1-5 100.0%  51.4%     KQG------------------YYLSEIQADAILRMSLRNLTGLD-QKEIIESYKNLMGKIIDFVDILSKPERIT    
10 Q47968/1-480    99.3%  54.6%     ---------------------FDFSEEQANHIVSMQLGSLTSME-AAEIEAEYEDVQATIERLETILGDQSELD    
11 O24814/1-472   100.0%  53.7%     ---------------------FELTERQSQAILDMRLRRLTGLE-RDKIQNEYDDLLALITDLADILAKPERVI    
12 GYRA_BACS5/1-4  99.8%  58.4%     ---------------------FELSYEQAQAILDMRLQRLTGLE-RDKIEAEYKELIERIAELKAILADHEKVL    
13 SARECF_3/1-473 100.0%  57.1%     ---------------------FKLSEKQAQAILDMRLRRLTGLE-RDKIEAEYNELLNYISELEAILADEEVLL    
14 GYRA_CLOAB/1-4 100.0%  60.4%     ---------------------FGLSEKQAQAILDLKLQRLTGLE-REKIEDEYNELMKTIAELKSILADENKIL    
15 MG09251_4/1-47  99.8%  52.4%     ---------------------FKLDEIQAKAVLDMRLRSLSVLE-VNKLQTEQKELKDSIEFCKKVLADQKLQL    
16 Q55738/1-477   100.0%  55.6%     ---------------------FSLSEVQADAILQMQLRRLTALE-ADKITAEHDELQTKIADFQDILARRERVN    
17 Q59784/1-498    99.8%  51.4%     ---------------------YNLSEIQARAILDLRLSSLTAMG-VKEVTDELAELAAKIRDYLDILGSRERIM    
18 GYRA_RICPR/1-4  99.8%  53.8%     ---------------------LSFTEVQAKAILEMKLQRLTAME-KEKLEQDLKHLATDIAEYLNILASRTRLL    
19 GYRA_MYCTU/1-4 100.0%  51.4%     ---------------------LDIDEIQAQAILDMQLRRLAALE-RQRIIDDLAKIEAEIADLEDILAKPERQR    
20 GYRA_STRCO/1-4  99.8%  53.2%     ---------------------LEIDEIQANAILEMQLRRLAALE-RQKIVREHDELQAKITEYNEILASPVRQR    
21 GYRA_BORBU/1-4 100.0%  54.0%     ---------------------FGLSEIQANSVLDMRLQKLTALE-IFKLEEELNILLSLIKDYEDILLNPVRII    
22 GYRA_TREPA/1-4 100.0%  49.9%     ---------------------FDFDNVQAQAIVDMQMKRLTGLE-VESLRTELKDLTELISSLEELLTSPQKVL    
23 GYRA_SYNY3/1-4 100.0%  48.8%     ---------------------LGISLQQGDAILGMPMRRITGLE-REKLQQEHTDLAQRIEQLETLIGDRQERL    
24 O67108/1-472    99.6%  54.4%     ---------------------FGLSEKQAQAVLDLRLQRLTSLE-REKLLEEEKELREKIEYYKKLVASEGERI    
25 O29785/1-466    98.9%  55.4%     ---------------------YSLSEKQADAVLQMRLQKLTAME-IDALLKEYESLKEKIAEYESILASPEKID    
26 O50510/1-474   100.0%  47.6%     ---------------------FSLSDVQTQYILDTPLRRLTKYD-RIELESEKDRLNAEIEELTRILDSDAELR    
27 PARC_ECOLI/1-4  98.5%  43.2%     ---------------------FGLTETQAEAILELKLRHLAKLE-EMKIRGEQSELEKERDQLQGILASERKMN    
28 PARC_HAEIN/1-4  98.5%  43.9%     ---------------------FNLSDEQADAILNLRLRHLAKLE-ENQLKAEQDELEKERLNLEAILGSERRLN    
29 PARC_NEIGO/1-4  99.3%  41.0%     ---------------------FGLTEIQAEDILEIRLRQLARLE-GFKLEKELNELREEQGRLNIFLGDENEKR    
30 PARC_CAUCR/1-4  99.1%  46.8%     ---------------------FGLTDIQADAILNTRLRQLAKLE-EMEIRREHAELVEERDGILAMLASEAKQW    
31 E1342381/1-471  99.1%  50.5%     ---------------------FKISAIQVEVILNTRLRSLQKLE-EHAIIDEHSNLQKQQAILEKILKNHKELW    
32 PARC_MYCGE/1-4  99.6%  41.3%     ---------------------FKFTFNQAEAIVSLRLYQLTNTD-IFELNQEQNELEKTVISSEQLIASEKARN    
33 PARC_MYCPN/1-4 100.0%  41.5%     ---------------------YAFTLNQAEAIVSLRLYQLTNTD-IKVLFAEQKELEQTIQTAERLIAKPQARN    
34 G3513507/1-476 100.0%  41.5%     ---------------------FKFSELQATAIAELRLYKLSRMD-QIEFQEEKKNLEIQIENCNKLLNDKWEFN    
35 PARC_BACSU/1-4  99.8%  49.7%     ---------------------YEFTEPQAEAIVSLQLYRLTNTD-ITALKEEAEELGKKIEELESILSNDKKLL    
36 PARC_STAAU/1-4  99.8%  46.2%     ---------------------YEFTEEQAEAIVMLQLYRLTNTD-IVALEGEHKELEALIKQLRHILDNHDALL    
37 PARC_STRPN/1-4  99.8%  45.3%     ---------------------YDFTEEQAEAIVTLQLYRLTNTD-VVVLQEEEAELREKIAMLAAIIGDERTMY    
38 PARC_BORBU/1-4  93.8%  25.8%     ---------------------REVLKEDVENLLKIPIRKISLFD-IDKNSKDIKILNKELKSINSNISSIRGYS    
39 O84667/1-455    93.8%  24.8%     ---------------------PAPDKQATAQLAALTIKKILCFD-ENSYEKELACLEKKRSSVQKDLSQLKKYT    
40 TOP5_BPT4/1-44  94.9%  22.2%     ---------------------SYVDKLVGMNIFHMTSDEAKKLAEEAKAKKEENEYWKTTDVVTEYTKDLEEIK    
41 O24308/1-483    90.7%  15.3%     SV-----------------SVEGATWGDYDDLLSLPIGTLTLES-VQKLLDEKTEKEKEYEILSGTPTTSLWLK    
42 Q23670/1-511    95.1%  15.8%     EEDE---------AISSAAKAVETKLSDYDYLVGMALIKLSEEE-KNKLIKESEEKMAEVRVIEKKTWQDLWHE    
43 P90520/1-499    92.9%  14.1%     QLTKRKSEHQSISSSDPKSLWTADLQQLKEYLEKSDKEFQKKPL-KTSSSSSFDVSSSSESAKLSSTRKSKTDK    
44 TOP2_TRYCR/1-4  93.2%  15.4%     --------------------------DSYDYVLRKPITFYTKTS-LENLNRKISETEKRIDKLKKTAPVQMWLD    
45 O41065/1-434    91.2%  18.9%     --------------------------GKYDYLLNMRISSLTLER-ATELEREAVKLNKELDDLSKTTETDMWNN    
46 TOP2_ARATH/1-5  95.4%  16.4%     -------------------SSSYIPGSEYDYLLAMAIASLTIEK-VEELLADRDKMIIAVADMKKTTPKSLWLS    
47 TOP2_SCHPO/1-4  93.8%  16.8%     --------------------------DAYNYLLSMPLWSLTYER-YVELLKKKDEVMAELDALIKKTPKELWLH    
48 TOP2_PLAFK/1-4  95.1%  18.2%     -------------------IIAGITVKDYDYLLSMPIFSLTLEK-VEDLLTQLKEKERELEILRNITVETMWLK    
49 O59864/1-494    95.1%  17.0%     -------------------DDTQDLAHAFDYLLGMAIWSLTQER-VEKLRRQIGEKEHEIDELIKLSSEDIWLR    
50 TOP2_DROME/1-5  95.1%  15.3%     SKAKKE-----KEVDPEKAFKKLTDVKKFDYLLGMSMWMLTEEK-KNELLKQRDTKLSELESLRKKTPEMLWLD    
51 TOP2_CRIFA/1-4  93.2%  16.9%     --------------------------DGYDYILKKPITFYTKTS-TEKLQADIKKTQDSIAVLKQTTPVKMWLT    
52 D1034930/1-511  94.7%  15.4%     ATR------KKDKDDESTVNGPEELFGTYEYLLGLKIWSLTKER-YEKLLKQKQEKETELENLLKLSAKDLWNN    
53 TP2B_MOUSE/1-4  95.1%  17.1%     ------------------SDSGTPSGPDFNYILNMSLWSLTKEK-VEELIKQRDTKGREVNDLKRKSPSDLWKE    
54 TOP2_YEAST/1-5  94.7%  15.4%     ES--------SHEDTENVINGPEELYGTYEYLLGMRIWSLTKER-YQKLLKQKQEKETELENLLKLSAKDIWNT    
55 TP2A_MOUSE/1-4  95.1%  17.3%     -----------------TSDSAAEAGPTFNYLLDMPLWYLTKEK-KDELCKQRNEKEQELNTLKQKSPSDLWKE    
56 CER05D3_1/1-48  93.8%  16.1%     ----------------------LNFQANYGYLLEMPVSRLTSDE-MKRLEERKSRRRTELEAAESADWKSVWRS    
57 TOP2_CANAL/1-5  94.5%  14.8%     DVGNTSVANIQEGEPEQAAHVPETIYSSYDYLLGMAIWSLTYER-FMRIMQQRDQKEAELNALLSKSAKDLWNQ    
58 O16140/1-511    94.7%  16.7%     PDPKGKP------VDPDKAFQQLKEVKKFNYLLGMSMWMLTKEK-KDELLKQRDQKLTELTTLKNKTAPMLWRE    
59 O61078/1-458    92.9%  14.1%     --------------------------DDYDYMLMNPITFYTKTS-GEKLQMQIEKTEIRMGVLKQTTPVKLWLR    
   consensus/100%                   ...............................h...................p......................    
   consensus/90%                    ...........................thp.llth.h..ls..p...tl.tp.tph.t.ht.h.th..p.....    
   consensus/80%                    ...........................phphllthtl.pLot.c.htcl.tphpph.tpltth.phhsp..hh.    
   consensus/70%                    .....................hths..phphlLphplhpLTthc.hpcl.p-hpch.ppltplpphhspp.hh.