Family alignment for the eIF2B_5 domain, displayed in 

                     cov    pid  1 [        .         .         .         .         :         .         .         . 80 
 1 IF2B_METTH/10- 100.0% 100.0%    TKRFEVPKAYSVIQGN-----RTFIQNFREVADALNRDP-----QHLLKFLLRELGTAGNLEG--GRAILQGKFTHFLIN    
 2 IF2B_METJA/18- 100.0%  55.6%    KDRFELPEIEILIEGN-----RTIIRNFRELAKAVNRDE-----EFFAKYLLKETGSAGNLEG--GRLILQRRISPELLK    
 3 IF2B_PYRAB/14- 100.0%  59.3%    KSRFEVPGALVTIEGN-----KTIIENFKDIAEALNRDP-----QHLLKFLLREIATAGTLEG--KRVVLQGRFTPYLIA    
 4 IF2B_ARCFU/11- 100.0%  46.3%    RERFEIPRVSIQREGA-----RTILKNFSQIAKTLNRSE-----DHLYKYIVKSLGTAGFIDN--GRLVLQGKFTESELQ    
 5 Q9HKJ3/11-132  100.0%  41.7%    IDRLKIPDPEIIREGK-----ATIIRNFQDIVDIINRDP-----EHIIKFLTREFGTNIVQNG--RRLIINRKLTLEELL    
 6 Q9DEQ6/183-311 100.0%  33.6%    KRKFVMKPPQVVRVGT----KKTSFVNFTDICKLLHRQP-----KHLLAFLLAELGTSGSIDGN-NQLVIKGRFQQKQIE    
 7 ENSP00000238/1 100.0%  31.8%    IRKFVMKPPQVVRVGT----KKTSFVNFTHICKLLHHQP-----KHLRAFLLAELGTSGSIDGN-NQLVIKGRFQQKQIE    
 8 IF2B_DROME/161 100.0%  34.5%    KPKFVMRPPQVLRVGT----KKTSFANFMDIAKTLHRLP-----KHLLDFLLAELGTSGSMDGN-QQLIIKGRFQPKQIE    
 9 IF2B_CAEEL/95- 100.0%  30.0%    KKKFAIKLPEVARAGS----KKTAFSNFLEICRLMKRQD-----KHVLQFLLAELGTTGSIDGS-NCLIVKGRWQQKQFE    
10 IF2B_YEAST/137  99.1%  29.5%    GPKFRIPPPVCLRDG-----KKTIFSNIQDIAEKLHRSP-----EHLIQYLFAELGTSGSVDGQ-KRLVIKGKFQSKQME    
11 IF2B_SCHPO/165  99.1%  30.0%    KRKYTIVPPSVHREG-----KKTIFANISDISKRMHRSL-----DHVIQFLFAELGTSGSVDGS-SRLIIKGRFQQKQIE    
12 13549158/124-2  99.1%  31.5%    RRRTVMRPPQVLREG----TKKTVFVNFMDLCKTMHRQP-----DHVMQYLLAELGTSGSLDGQ-QRLVVKGRFAPKNFE    
13 IF2B_MALDO/161  99.1%  33.3%    RRRTVMRPPQVLREG----TKKAVFVNFMDLCKTMHRQP-----DHVMAFLLAELGTSGSLDGQ-QRLVVKGRFAPKNFE    
14 IF2B_WHEAT/124  99.1%  33.3%    RRRTVMRPPQVLREG----TKKTVFVNFMDLCKTMHRQP-----EHVMMFLLAEMGTSGSLDGQ-QRLVIKGRFAPKNFE    
15 Q9SFC2/22-150  100.0%  22.8%    WLLTIIWPPQVLREETAKGTKKTVFVNFMDYCKTMHRNP-----DHVMAFLLAELGTRGKLDDQ-QRLVVRGRFTQRDFE    
16 Q9LZV2/81-207   99.1%  24.4%    RPRTVMMPPQLLAEG-----TITVCLNFADLCRTMHRKP-----DHVMKFLLAQMETKVSLNKQ-QRLEIKGLVSSKDFQ    
17 AAK39892/17-15 100.0%  26.8%    CSKLIIPIPKVFREGS----KKTVYKNFLDTTEKLNRDK-----DHLISFICNELRTYASIQEG-GGLAIKGRFNEKDIQ    
18 Q9HQ97/9-131   100.0%  41.3%    ETRFEVPDPNVRKEGN-----VTVYENFQATLDALSRTQ-----DHVLKFLQNEVGTSASIDES-GRARLTGEFGQRRVS    
19 IF2B_AERPE/27- 100.0%  37.3%    TSEYRIPEPQIIRIGS-----QTVIRNFREIAQALKRDP-----KLVARYLQKELATAASYEEESGQLILNVKVSRKVVN    
20 AAK42529/13-13 100.0%  33.0%    EGTQSLPNMIILNIGN-----TTIIRNFAEYCDRIRRED-----KICMKYLLKELAAPGNVDDK-GELVIQGKFSSQVIN    
21 IF5_HUMAN/1-13 100.0%  27.6%    FYRYKMPRLIAKVEGKGN-GIKTVIVNMVDVAKALNRPP-----TYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQ    
22 Q9VXK6/1-131   100.0%  24.1%    FYRYKMPRLQAKVEGKGN-GIKTVLVNMAEVARAIGRPA-----TYPTKYFGCELGAQTLFDHKNERFVVNGSHDVNKLQ    
23 IF5_CAEEL/1-13 100.0%  27.7%    FYRYKMPKLSAKVEGKGN-GIKTVISNMSEIAKALERPPMCMFIANPTKYFGCELGAQTNFDAKNERYIVNGEHDANKLQ    
24 IF5_SCHPO/1-13 100.0%  27.6%    FYRYRMPKLQSKIEGKGN-GIKTVIPNMSDIAKALGRPP-----LYVTKFFGFELGAQTTIIADMDRYIVNGAHDAGKLQ    
25 IF5_YEAST/1-12 100.0%  25.2%    FYRYKMPPIQAKVEGRGN-GIKTAVLNVADISHALNRPA-----PYIVKYFGFELGAQTSISVDKDRYLVNGVHEPAKLQ    
26 IF5_PHAVU/1-13 100.0%  25.2%    FYRYKMPRMVTKIEGRGN-GIKTNVVNMVDIAKRLARPA-----SYTTKYFGCELGAQSKFDEKTGTSHVNGAHETAKLA    
27 Q9SBX1/1-131   100.0%  26.1%    FYRYKMPRMITKIEGRGN-GIKTNVVNMVDIAKALARPA-----SYTTKYFGCELGAQSKFDEKTGISLVNGAHDTAKLA    
28 12322505/1-131 100.0%  27.0%    FYRYKMPRMMTKIEGRGN-GIKTNVVNMVEIAKALGRPA-----AYTTKYFGCELGAQSKFDEKNGTSLVNGAHDTSKLA    
29 Q9S825/1-131   100.0%  30.4%    FYRYKMPKMVTKTEGKGN-GIKTNIINNVEIAKALARPP-----SYTTKYFGCELGAQSKFDEKTGTSLVNGAHNTSKLA    
   consensus/100%                  .....h........t.......s.h.N..th.phht+..........h.ah..phts........t...lph.ht...h.    
   consensus/90%                   h.ch.h....hhh.G......tT.h.Nh.chschhtR.......th.htahhtEhusts.hpt..tp.hlpstht.t.ht    
   consensus/80%                   h.+h.h....hhhtG......+T.h.Nh.-lscthtR.s.....pahhpahhtElGstsph-tt.tphllpGtap.tpht    
   consensus/70%                   h.+ahh....shhEGp....hKTshhNhh-ls+tlpR.s.....pahhpahhtELGspush-tp.tphllpGpap.pplp    

                     cov    pid 81          .         1         .         .         .       ] 138
 1 IF2B_METTH/10- 100.0% 100.0%    ERIEDYVNKFVICHECNRPDTRIIRE--GRISLLKCE----------------ACGAK    
 2 IF2B_METJA/18- 100.0%  55.6%    SRINDFLREYVICRECGKPDTKIIKE--GRVHLLKCM----------------ACGAI    
 3 IF2B_PYRAB/14- 100.0%  59.3%    NKIKKYIKEYVICPVCGSPDTKIIKR--DRFYFLKCE----------------ACGAE    
 4 IF2B_ARCFU/11- 100.0%  46.3%    KEVDDYVRLYVLCRECNSPDTEFIKE--ERVLMLRCL----------------ACGAK    
 5 Q9HKJ3/11-132  100.0%  41.7%    DKMNEYINTYVRCYECGSLDTEIQKS--GRISLLVCK----------------ACGAQ    
 6 Q9DEQ6/183-311 100.0%  33.6%    NVLRRYIKEYVTCHTCRSPDTILQKD--TRLYFLQCE----------------TCHSR    
 7 ENSP00000238/1 100.0%  31.8%    NVLRRYIKEYVTCHTCRLLDTILQKD--MRIYFLQCE----------------TCHSR    
 8 IF2B_DROME/161 100.0%  34.5%    NVLRRYIKEYVTCHTCRSPETILQKD--TRLFFLQCE----------------SCGSR    
 9 IF2B_CAEEL/95- 100.0%  30.0%    SVLRKYIKEYVMCHTCKSPETQLTKD--TRLFFLQCT----------------NCGSR    
10 IF2B_YEAST/137  99.1%  29.5%    NVLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCK----------------SCGST    
11 IF2B_SCHPO/165  99.1%  30.0%    NVLRRYIVEYVTCKTCKSPDTILTKE--NRIFFMTCE----------------ACGSV    
12 13549158/124-2  99.1%  31.5%    GILRRYITDYVICLGCKSPDTILSKE--NRLFFLRCE----------------KCGSQ    
13 IF2B_MALDO/161  99.1%  33.3%    GILRRYVNEYVICLGCQSPDTILSKE--NRLFFLRCE----------------KCGSG    
14 IF2B_WHEAT/124  99.1%  33.3%    AILRRYINEYVICHGCKSPDTILSKE--NRLFFLRCE----------------QCGSS    
15 Q9SFC2/22-150  100.0%  22.8%    SLLRGYILDYVMCIPCKSTEAILSKE--NRLFFLRCG--KVKLYPISF-----SCLGQ    
16 Q9LZV2/81-207   99.1%  24.4%    AVFRKYIDAFVICVCCKSPDTALAEE-GNGLFNLRCETGKDEDKLVSFESVLVQCGLV    
17 AAK39892/17-15 100.0%  26.8%    KIMRIYIPDYVLCKSCNSWKTDLRKDIITRLYFMDCK----------------TCGAS    
18 Q9HQ97/9-131   100.0%  41.3%    DTLDAYVETYVTCPECGLPDTNLETD--GDTIQLHCE----------------ACGAR    
19 IF2B_AERPE/27- 100.0%  37.3%    QFLQLFMKTYVRCPTCGSIDTKLLRQ--ERAYMLKCE----------------ACGAE    
20 AAK42529/13-13 100.0%  33.0%    TLMERFLKAYVECSTCKSLDTILKKE--KKSWYIVCL----------------ACGAQ    
21 IF5_HUMAN/1-13 100.0%  27.6%    DMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCK----------------ACGYR    
22 Q9VXK6/1-131   100.0%  24.1%    DLLDGFIRKFVLCPECDNPETNLTVSAKNQTISQSCK----------------ACGFH    
23 IF5_CAEEL/1-13 100.0%  27.7%    DILDGFIKKFVLCKSCENPETQLFVR--KNNIKSKCK----------------ACGCS    
24 IF5_SCHPO/1-13 100.0%  27.6%    DLLDVFIRRFVLCASCQNPETELSINKKDQTISYDCK----------------ACGYR    
25 IF5_YEAST/1-12 100.0%  25.2%    DVLDGFINKFVLCGSCKNPETEIIIT-KDNDLVRDCK----------------ACGKR    
26 IF5_PHAVU/1-13 100.0%  25.2%    GLLEIFIKKYVQCYGCGNPETEILIT-KNQMIQLKCA----------------ACGFV    
27 Q9SBX1/1-131   100.0%  26.1%    GLLEVFIKKYVQCYGCGNPETEILIS-KTQMISLKCA----------------ACGFV    
28 12322505/1-131 100.0%  27.0%    GLLENFIKKYVQCYGCGNPETEILIT-KTQMLQLKCA----------------ACGFL    
29 Q9S825/1-131   100.0%  30.4%    GLLENFIKKFVQCYGCGNPETEIIIT-KTQMVNLKCA----------------ACGFI    
   consensus/100%                  t.hp.ah..aV.C..Ct..ps.h..p...t.....C.................tCh..    
   consensus/90%                   thhp.al.taV.C.tCtp.-T.l.hp..tp.h...C.................tCt..    
   consensus/80%                   shlctalppaVhC.tCts.-T.l.hp..pphh.hpCt................sCG..    
   consensus/70%                   slLctaIpcYVhChsCtsP-T.l.hp..sphhhlpCp................uCGtp