Domains within Homo sapiens protein A0A024QZ42_HUMAN (A0A024QZ42)

HCG1985580, isoform CRA_c

Alternative representations: 1 /

Protein length121 aa
Source databaseUniProt
Identifiers A0A024QZ42_HUMAN, A0A024QZ42, ENSP00000485024.1, ENSP00000485024, A0A2K6BNU6_MACNE, A0A2K6BNU6, A0A2K6RU48_RHIRO, A0A2K6RU48, A0A2K5ZR67_MANLE, A0A2K5ZR67, A0A0D9RXX8_CHLSB, A0A0D9RXX8
Source gene ENSG00000249915
Alternative splicing PDCD6_HUMAN, ENSP00000422085.1, Q86W51_HUMAN, ENSP00000423815.1, D6RA21_HUMAN, E7EPW6_HUMAN, ENSP00000425370.1, A0A024QZ42_HUMAN, A0A087WZ38_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

A0A024QZ42_HUMAN is shown as PDCD6 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for PDCD6

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 37548.ENSCAPP00000011148 in eggNOG.

OGTaxonomic classDescription
LKOG0037All organisms (root)peflin,calcium-binding protein CML,programmed cell death protein 6
KOG0037Eukaryota (superkingdom)peflin,calcium-binding protein CML,programmed cell death protein 6
HU85WMetazoa (kingdom)programmed cell death protein 6,peflin
93RXIChordata (phylum)programmed cell death protein 6,peflin
5R7AVSarcopterygii (superclass)programmed cell death protein 6,peflin
8Z3XTMammalia (class)programmed cell death protein 6,peflin
4R5QWEuarchontoglires (superorder)peflin,programmed cell death protein 6
AI040Rodentia (order)programmed cell death protein 6
EVIHEHystricomorpha (suborder)programmed cell death protein 6
H5YTCBilateria (clade)programmed cell death protein 6,peflin
7KDKHOpisthokonta (clade)programmed cell death protein 6,peflin
9FY64Vertebrata (clade)programmed cell death protein 6,peflin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: