Domains within Homo sapiens protein A0A024RCR1_HUMAN (A0A024RCR1)

Tripartite motif-containing 39, isoform CRA_a

Alternative representations: 1 /

Protein length488 aa
Source databaseUniProt
Identifiers A0A024RCR1_HUMAN, A0A024RCR1, ENSP00000389198.1, ENSP00000389198, ENSP00000398956.1, ENSP00000398956, ENSP00000389852.2, ENSP00000389852, ENSP00000392130.1, ENSP00000392130, ENSP00000404904.1, ENSP00000404904, ENSP00000401071.2, ENSP00000401071, ENSP00000414525.1, ENSP00000414525, ENSP00000401184.2, ENSP00000401184, ENSP00000415259.1, ENSP00000415259, ENSP00000379800.3, ENSP00000379800, ENSP00000379797.1, ENSP00000379797, ENSP00000365847.5, ENSP00000365847, ENSP00000404340.1, ENSP00000404340, ENSP00000412743.1, ENSP00000412743, ENSP00000396986.2, ENSP00000396986, ENSP00000411582.1, ENSP00000411582, ENSP00000394353.1, ENSP00000394353, ENSP00000387445.2, ENSP00000387445, ENSP00000373095.2, ENSP00000373095, ENSP00000383486.1, ENSP00000383486, ENSP00000373097.4, ENSP00000373097, F7HEN1_MACMU, F7HEN1, K7BL16_PANTR, K7BL16, A0A2K5P025_CERAT, A0A2K5P025, A0A2I2ZEV0_GORGO, A0A2I2ZEV0, A0A2K5WSG2_MACFA, A0A2K5WSG2, H2PIE3_PONAB, H2PIE3, A0A0D9R725_CHLSB, A0A0D9R725, A0A2K6MF34_RHIBE, A0A2K6MF34, A0A2K6Q9R4_RHIRO, A0A2K6Q9R4, A0A2K5HYU8_COLAP, A0A2K5HYU8, A0A2I3GZN4_NOMLE, A0A2I3GZN4, Q9HCM9-2, H9F1N6_MACMU, H9F1N6
Source gene ENSG00000204599
Alternative splicing ENSP00000406034.1, A2AAZ4_HUMAN, A0A024RCR1_HUMAN, ENSP00000415414.1, ENSP00000413846.1, ENSP00000388852.1, TRI39_HUMAN, H0Y735_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Predicted functional partners

A0A024RCR1_HUMAN is shown as TRIM39 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for TRIM39

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 60711.ENSCSAP00000004414 in eggNOG.

OGTaxonomic classDescription
LKOG2177All organisms (root)butyrophilin,tripartite motif-containing protein 2/3,deltex [EC:2.3.2.27]
KOG2177Eukaryota (superkingdom)butyrophilin,tripartite motif-containing protein 2/3,deltex [EC:2.3.2.27]
HVPGDMetazoa (kingdom)butyrophilin,tripartite motif-containing protein 35,tripartite motif-containing protein 2/3
93S94Chordata (phylum)butyrophilin,tripartite motif-containing protein 35,tripartite motif-containing protein 16
5R91JSarcopterygii (superclass)butyrophilin,inducible T-cell co-stimulator ligand,tripartite motif-containing protein 39 [EC:2.3.2.27]
8ZBB5Mammalia (class)tripartite motif-containing protein 75,tripartite motif-containing protein 39 [EC:2.3.2.27],tripartite motif-containing protein 60/61
4RCACEuarchontoglires (superorder)tripartite motif-containing protein 39 [EC:2.3.2.27]
4ZRGUPrimates (order)tripartite motif-containing protein 39 [EC:2.3.2.27]
98IYVHaplorrhini (suborder)tripartite motif-containing protein 39 [EC:2.3.2.27]
BV3SUSimiiformes (infraorder)tripartite motif-containing protein 39 [EC:2.3.2.27]
9EFXICatarrhini (parvorder)tripartite motif-containing protein 39 [EC:2.3.2.27]
9FXMTVertebrata (clade)tripartite motif-containing protein 35,butyrophilin,tripartite motif-containing protein 16
7KUB7Opisthokonta (clade)butyrophilin,tripartite motif-containing protein 35,tripartite motif-containing protein 2/3
H6GQGBilateria (clade)butyrophilin,tripartite motif-containing protein 35,tripartite motif-containing protein 2/3
6I0Z2Cercopithecidae (family)tripartite motif-containing protein 39 [EC:2.3.2.27]
BRCEFCercopithecinae (subfamily)tripartite motif-containing protein 39 [EC:2.3.2.27]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: