Domains within Mus musculus protein A0A087WPA7_MOUSE (A0A087WPA7)

Transcriptional activator Myb

Alternative representations: 1 /

Protein length755 aa
Source databaseUniProt
Identifiers A0A087WPA7_MOUSE, A0A087WPA7, ENSMUSP00000139699.1, ENSMUSP00000139699
Source gene ENSMUSG00000019982
Alternative splicing A0A087WPA7_MOUSE, MYB_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

A0A087WPA7_MOUSE is shown as Myb in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Myb

Protein A0A087WPA7_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04218Cellular senescence
map04151PI3K-Akt signaling pathway

KEGG orthologous groups

KONameDescription
K09422MYBPtranscription factor MYB, plant
K09421MYBL1, A-MYBmyb-related protein A
K09420MYB, C-MYBtranscriptional activator Myb

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 3 PTMs annotated in this protein:

PTMCount
Phosphorylation1
Ubiquitination1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Myb.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000139699 in eggNOG.

OGTaxonomic classDescription
LKOG0048All organisms (root)transcription factor MYB, plant,transcriptional activator Myb,Myb-like DNA-binding protein FlbD
KOG0048Eukaryota (superkingdom)transcription factor MYB, plant,transcriptional activator Myb,Myb-like DNA-binding protein FlbD
HVUFVMetazoa (kingdom)myb-related protein A,transcriptional activator Myb,myb-related protein B
93KEXChordata (phylum)myb-related protein A,transcriptional activator Myb,myb-related protein B
5R2PRSarcopterygii (superclass)transcriptional activator Myb
8Z0F2Mammalia (class)transcriptional activator Myb
4RCT3Euarchontoglires (superorder)transcriptional activator Myb
AI8XWRodentia (order)transcriptional activator Myb
8DAF8Myomorpha (suborder)transcriptional activator Myb
9FAJRVertebrata (clade)transcriptional activator Myb
7GHJ4Opisthokonta (clade)transcriptional activator Myb,myb-related protein A,myb-related protein B
H57VFBilateria (clade)myb-related protein A,transcriptional activator Myb,myb-related protein B
CQ64TMuridae (family)transcriptional activator Myb
AE6HFMurinae (subfamily)transcriptional activator Myb
5PGH0Mus (genus)transcriptional activator Myb
HE3VIMus (subgenus)transcriptional activator Myb

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: