Domains within Homo sapiens protein A0A087X0X3_HUMAN (A0A087X0X3)

Heterogeneous nuclear ribonucleoprotein M

Alternative representations: 1 /

Protein length730 aa
Source databaseUniProt
Identifiers A0A087X0X3_HUMAN, A0A087X0X3, ENSP00000483715.1, ENSP00000483715, H2QF86_PANTR, H2QF86, G3RQE1_GORGO, G3RQE1, A0A2K5X846_MACFA, A0A2K5X846, A0A2K5MG10_CERAT, A0A2K5MG10, A0A2K6A879_MANLE, A0A2K6A879
Source gene ENSG00000099783
Alternative splicing ENSP00000325732.2, HNRPM_HUMAN, M0R019_HUMAN, M0R0Y6_HUMAN, ENSP00000472789.1, M0QYQ7_HUMAN, M0R0N3_HUMAN, M0QYL3_HUMAN, M0QZM1_HUMAN, M0R2I7_HUMAN, M0QY96_HUMAN, A0A087X0X3_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

A0A087X0X3_HUMAN is shown as HNRNPM in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for HNRNPM

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9598.ENSPTRP00000017736 in eggNOG.

OGTaxonomic classDescription
LCOG0724All organisms (root)serine/arginine-rich splicing factor 4/5/6,serine/arginine-rich splicing factor 1,cleavage stimulation factor subunit 2
KOG4212Eukaryota (superkingdom)myelin expression factor 2,heterogeneous nuclear ribonucleoprotein M,mitochondrial import inner membrane translocase subunit TIM44
HUBEGMetazoa (kingdom)myelin expression factor 2,heterogeneous nuclear ribonucleoprotein M,mitochondrial import inner membrane translocase subunit TIM44
94WCHChordata (phylum)heterogeneous nuclear ribonucleoprotein M,mitochondrial import inner membrane translocase subunit TIM44
5R6UZSarcopterygii (superclass)heterogeneous nuclear ribonucleoprotein M,mitochondrial import inner membrane translocase subunit TIM44
8YV7MMammalia (class)heterogeneous nuclear ribonucleoprotein M
4RJA0Euarchontoglires (superorder)heterogeneous nuclear ribonucleoprotein M
4ZUXDPrimates (order)heterogeneous nuclear ribonucleoprotein M
98EG1Haplorrhini (suborder)heterogeneous nuclear ribonucleoprotein M
BVAB4Simiiformes (infraorder)heterogeneous nuclear ribonucleoprotein M
9EX3VCatarrhini (parvorder)heterogeneous nuclear ribonucleoprotein M
H4SRFBilateria (clade)myelin expression factor 2,heterogeneous nuclear ribonucleoprotein M,mitochondrial import inner membrane translocase subunit TIM44
7K55SOpisthokonta (clade)myelin expression factor 2,heterogeneous nuclear ribonucleoprotein M,mitochondrial import inner membrane translocase subunit TIM44
9GQ5XVertebrata (clade)heterogeneous nuclear ribonucleoprotein M,mitochondrial import inner membrane translocase subunit TIM44
FXDVTHominoidea (superfamily)heterogeneous nuclear ribonucleoprotein M
5N3PUHominidae (family)heterogeneous nuclear ribonucleoprotein M
5Y6BKHomininae (subfamily)heterogeneous nuclear ribonucleoprotein M

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: