Domains within Homo sapiens protein A0A0A0MQT4_HUMAN (A0A0A0MQT4)

DDB1- and CUL4-associated factor 10

Alternative representations: 1 /

Protein length386 aa
Source databaseUniProt
Identifiers A0A0A0MQT4_HUMAN, A0A0A0MQT4, ENSP00000242323.8, ENSP00000242323, A0A2J8QRH5_PANTR, A0A2J8QRH5, G1QTI4_NOMLE, G1QTI4
Source gene ENSG00000122741
Alternative splicing DCA10_HUMAN, A0A0A0MQT4_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

A0A0A0MQT4_HUMAN is shown as DCAF10 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for DCAF10

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 61853.ENSNLEP00000004252 in eggNOG.

OGTaxonomic classDescription
LKOG4155All organisms (root)WD repeat-containing protein 61,rabconnectin-3b,apoptotic protease-activating factor
KOG4155Eukaryota (superkingdom)WD repeat-containing protein 61,rabconnectin-3b,apoptotic protease-activating factor
HVQCPMetazoa (kingdom)DDB1- and CUL4-associated factor 10
94Q1YChordata (phylum)DDB1- and CUL4-associated factor 10
5QWRDSarcopterygii (superclass)DDB1- and CUL4-associated factor 10
8YV7DMammalia (class)DDB1- and CUL4-associated factor 10
4RH0BEuarchontoglires (superorder)DDB1- and CUL4-associated factor 10
4ZZDRPrimates (order)DDB1- and CUL4-associated factor 10
98S4XHaplorrhini (suborder)DDB1- and CUL4-associated factor 10
BVFP8Simiiformes (infraorder)DDB1- and CUL4-associated factor 10
9EM97Catarrhini (parvorder)DDB1- and CUL4-associated factor 10
7GUQ5Opisthokonta (clade)DDB1- and CUL4-associated factor 10
9GAT5Vertebrata (clade)DDB1- and CUL4-associated factor 10
H3HM1Bilateria (clade)DDB1- and CUL4-associated factor 10
FX2JBHominoidea (superfamily)DDB1- and CUL4-associated factor 10

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: