Domains within Drosophila melanogaster protein A0A0B4KI34_DROME (A0A0B4KI34)

CIN85 and CD2AP related, isoform J

Alternative representations: 1 /

Protein length941 aa
Source databaseUniProt
Identifiers A0A0B4KI34_DROME, A0A0B4KI34, FBPP0302572, Q9Y154_DROME, Q9Y154, A0A0B4KHG1_DROME, A0A0B4KHG1
Source gene FBgn0027598
Alternative splicing Q9VA35_DROME, FBpp0085068, A0A0B4KHJ8_DROME, FBpp0301771, A0A0B4KI34_DROME, FBpp0085067, FBpp0301769, Q9VA36_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

A0A0B4KI34_DROME is shown as cindr in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for cindr

Protein A0A0B4KI34_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05100Bacterial invasion of epithelial cells

KEGG orthologous groups

KONameDescription
K13738CD2APCD2-associated protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0302572 in eggNOG.

OGTaxonomic classDescription
EIF0REndopterygota (cohort)SH3 domain-containing protein 21
LKOG4348All organisms (root)CD2-associated protein,SH3 domain-containing kinase-binding protein 1,SH3 domain-containing protein 21
FDUDUmelanogaster subgroup (species subgroup)SH3_9
FUZFYmelanogaster group (species group)SH3_9
KOG4348Eukaryota (superkingdom)CD2-associated protein,SH3 domain-containing kinase-binding protein 1,SH3 domain-containing protein 21
HSNHZMetazoa (kingdom)CD2-associated protein,SH3 domain-containing kinase-binding protein 1,SH3 domain-containing protein 21
HIRXMArthropoda (phylum)SH3 domain-containing protein 21
8668THexapoda (subphylum)SH3 domain-containing protein 21
AHFUXNeoptera (infraclass)SH3 domain-containing protein 21
AP3X6Diptera (order)SH3_9
7GVZIOpisthokonta (clade)CD2-associated protein,SH3 domain-containing kinase-binding protein 1,SH3 domain-containing protein 21
H4C3QBilateria (clade)CD2-associated protein,SH3 domain-containing kinase-binding protein 1,SH3 domain-containing protein 21
EGWT8Drosophila (genus)SH3_9
50KFWSophophora (subgenus)SH3_9

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: