Domains within Mus musculus protein A0A0G2JGW6_MOUSE (A0A0G2JGW6)

Cyclin-dependent kinase-like 5

Alternative representations: 1 /

Protein length960 aa
Source databaseUniProt
Identifiers A0A0G2JGW6_MOUSE, A0A0G2JGW6, ENSMUSP00000143726.1, ENSMUSP00000143726
Source gene ENSMUSG00000031292
Alternative splicing A0A0G2JF79_MOUSE, A0A0G2JFE2_MOUSE, CDKL5_MOUSE, A0A0G2JGW6_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

A0A0G2JGW6_MOUSE is shown as Cdkl5 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Cdkl5

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10096.MGP_SPRETEiJ_P0097021 in eggNOG.

OGTaxonomic classDescription
LKOG0593All organisms (root)cyclin-dependent kinase-like [EC:2.7.11.22],kinase [EC:2.7.1.-],cyclin-dependent kinase 2 [EC:2.7.11.22]
KOG0593Eukaryota (superkingdom)cyclin-dependent kinase-like [EC:2.7.11.22],kinase [EC:2.7.1.-],cyclin-dependent kinase 2 [EC:2.7.11.22]
HV7XUMetazoa (kingdom)cyclin-dependent kinase-like [EC:2.7.11.22]
94244Chordata (phylum)cyclin-dependent kinase-like [EC:2.7.11.22]
5QQVJSarcopterygii (superclass)cyclin-dependent kinase-like [EC:2.7.11.22]
8YUAWMammalia (class)cyclin-dependent kinase-like [EC:2.7.11.22]
4RQX6Euarchontoglires (superorder)cyclin-dependent kinase-like [EC:2.7.11.22]
AI7K6Rodentia (order)cyclin-dependent kinase-like [EC:2.7.11.22]
8DGY8Myomorpha (suborder)cyclin-dependent kinase-like [EC:2.7.11.22]
H6VCVBilateria (clade)cyclin-dependent kinase-like [EC:2.7.11.22]
7K0YTOpisthokonta (clade)cyclin-dependent kinase-like [EC:2.7.11.22]
9GPIJVertebrata (clade)cyclin-dependent kinase-like [EC:2.7.11.22]
CQ8GEMuridae (family)cyclin-dependent kinase-like [EC:2.7.11.22]
AE6A9Murinae (subfamily)cyclin-dependent kinase-like [EC:2.7.11.22]
5PJK7Mus (genus)cyclin-dependent kinase-like [EC:2.7.11.22]
HEB4CMus (subgenus)cyclin-dependent kinase-like [EC:2.7.11.22]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: