Domains within Homo sapiens protein A0A0U1RQQ9_HUMAN (A0A0U1RQQ9)

SCY1-like protein 2

Alternative representations: 1 /

Protein length933 aa
Source databaseUniProt
Identifiers A0A0U1RQQ9_HUMAN, A0A0U1RQQ9, ENSP00000489123.1, ENSP00000489123
Source gene ENSG00000136021
Alternative splicing ENSP00000448366.1, ENSP00000450294.1, A0A0U1RQQ9_HUMAN, SCYL2_HUMAN, H0YIK6_HUMAN, H0YI32_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

A0A0U1RQQ9_HUMAN is shown as SCYL2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SCYL2

Protein A0A0U1RQQ9_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map00310Lysine degradation iPath3
Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

KONameDescription
K17541SCYL2SCY1-like protein 2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000489123 in eggNOG.

OGTaxonomic classDescription
LKOG2137All organisms (root)SCY1-like protein 2,[histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
KOG2137Eukaryota (superkingdom)SCY1-like protein 2,[histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
HUBB0Metazoa (kingdom)SCY1-like protein 2,[histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
93PZGChordata (phylum)SCY1-like protein 2,[histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
5QGZISarcopterygii (superclass)SCY1-like protein 2
8ZC98Mammalia (class)SCY1-like protein 2
4R1SBEuarchontoglires (superorder)SCY1-like protein 2
4ZXREPrimates (order)SCY1-like protein 2
98IEIHaplorrhini (suborder)SCY1-like protein 2
BV7K2Simiiformes (infraorder)SCY1-like protein 2
9EX27Catarrhini (parvorder)SCY1-like protein 2
H68E5Bilateria (clade)SCY1-like protein 2,[histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
9FU7XVertebrata (clade)SCY1-like protein 2
7N311Opisthokonta (clade)SCY1-like protein 2,[histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
FXA32Hominoidea (superfamily)SCY1-like protein 2
5N9WZHominidae (family)SCY1-like protein 2
5XYUSHomininae (subfamily)SCY1-like protein 2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: