Domains within Homo sapiens protein A0A1U9X8V5_HUMAN (A0A1U9X8V5)

ZFP57

Alternative representations: 1 /

Protein length536 aa
Source databaseUniProt
Identifiers A0A1U9X8V5_HUMAN, A0A1U9X8V5, ENSP00000448351.1, ENSP00000448351, ENSP00000450279.1, ENSP00000450279, ENSP00000418259.1, ENSP00000418259, ENSP00000446798.1, ENSP00000446798, ENSP00000449407.1, ENSP00000449407, ENSP00000447495.1, ENSP00000447495, ENSP00000449230.1, ENSP00000449230, A0A1U9X8V4, Q9NU63-3
Source gene ENSG00000223852
Alternative splicing Q9NU63-2, ZFP57_HUMAN, A0A1U9X8V5_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Amniota

Predicted functional partners

A0A1U9X8V5_HUMAN is shown as ZFP57 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ZFP57

Protein A0A1U9X8V5_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05168Herpes simplex virus 1 infection

KEGG orthologous groups

KONameDescription
K09228KRABKRAB domain-containing zinc finger protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000418259 in eggNOG.

OGTaxonomic classDescription
LKOG1721All organisms (root)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
KOG1721Eukaryota (superkingdom)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
HT3YVMetazoa (kingdom)KRAB domain-containing zinc finger protein
947R4Chordata (phylum)KRAB domain-containing zinc finger protein
5R0NZSarcopterygii (superclass)KRAB domain-containing zinc finger protein
8Z8AJMammalia (class)KRAB domain-containing zinc finger protein
4RA6XEuarchontoglires (superorder)KRAB domain-containing zinc finger protein
4ZVWXPrimates (order)KRAB domain-containing zinc finger protein
98CZ3Haplorrhini (suborder)KRAB domain-containing zinc finger protein
BUY7FSimiiformes (infraorder)KRAB domain-containing zinc finger protein
9EQNRCatarrhini (parvorder)KRAB domain-containing zinc finger protein
7M2AHOpisthokonta (clade)KRAB domain-containing zinc finger protein
H4R2NBilateria (clade)KRAB domain-containing zinc finger protein
9FD5UVertebrata (clade)KRAB domain-containing zinc finger protein
FX67WHominoidea (superfamily)KRAB domain-containing zinc finger protein
5MXPCHominidae (family)KRAB domain-containing zinc finger protein
5Y0Y3Homininae (subfamily)KRAB domain-containing zinc finger protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: