Domains within Mus musculus protein A2AIR5_MOUSE (A2AIR5)

Glutamate receptor ionotropic, NMDA3A

Alternative representations: 1 /

Protein length1135 aa
Source databaseUniProt
Identifiers A2AIR5_MOUSE, A2AIR5, ENSMUSP00000091381.4, ENSMUSP00000091381, Q69Z52_MOUSE, Q69Z52
Source gene ENSMUSG00000039579
Alternative splicing A2AIR5_MOUSE, A2AIR4_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

A2AIR5_MOUSE is shown as Grin3a in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Grin3a

Protein A2AIR5_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04724Glutamatergic synapse
map05031Amphetamine addiction
map05034Alcoholism

KEGG orthologous groups

KONameDescription
K05210GRIN2Bglutamate receptor ionotropic, NMDA 2B
K05213GRIN3Aglutamate receptor ionotropic, NMDA 3A

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000091381 in eggNOG.

OGTaxonomic classDescription
LKOG1053All organisms (root)glutamate receptor ionotropic, NMDA 2B,glutamate receptor ionotropic, NMDA 3A,glutamate receptor ionotropic, NMDA 2C
KOG1053Eukaryota (superkingdom)glutamate receptor ionotropic, NMDA 2B,glutamate receptor ionotropic, NMDA 3A,glutamate receptor ionotropic, NMDA 2C
HTK3NMetazoa (kingdom)glutamate receptor ionotropic, NMDA 3A,glutamate receptor ionotropic, NMDA 3B,serine/threonine-protein phosphatase 2B regulatory subunit
94UNIChordata (phylum)glutamate receptor ionotropic, NMDA 3A,glutamate receptor ionotropic, NMDA 3B,serine/threonine-protein phosphatase 2B regulatory subunit
5QXNRSarcopterygii (superclass)glutamate receptor ionotropic, NMDA 3A,serine/threonine-protein phosphatase 2B regulatory subunit
8ZH8AMammalia (class)glutamate receptor ionotropic, NMDA 3A,serine/threonine-protein phosphatase 2B regulatory subunit
4RMBBEuarchontoglires (superorder)glutamate receptor ionotropic, NMDA 3A,serine/threonine-protein phosphatase 2B regulatory subunit
AI864Rodentia (order)glutamate receptor ionotropic, NMDA 3A,serine/threonine-protein phosphatase 2B regulatory subunit
8DG14Myomorpha (suborder)glutamate receptor ionotropic, NMDA 3A,serine/threonine-protein phosphatase 2B regulatory subunit
H3IE3Bilateria (clade)glutamate receptor ionotropic, NMDA 3A,glutamate receptor ionotropic, NMDA 3B,serine/threonine-protein phosphatase 2B regulatory subunit
7IK2MOpisthokonta (clade)glutamate receptor ionotropic, NMDA 3A,glutamate receptor ionotropic, NMDA 3B,serine/threonine-protein phosphatase 2B regulatory subunit
9GI6IVertebrata (clade)glutamate receptor ionotropic, NMDA 3A,serine/threonine-protein phosphatase 2B regulatory subunit
CQH3TMuridae (family)glutamate receptor ionotropic, NMDA 3A
AE5I5Murinae (subfamily)glutamate receptor ionotropic, NMDA 3A
5PWJWMus (genus)glutamate receptor ionotropic, NMDA 3A
HEAJWMus (subgenus)glutamate receptor ionotropic, NMDA 3A

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: