Domains within Mus musculus protein A2AKD7_MOUSE (A2AKD7)

Alpha-1-syntrophin

Alternative representations: 1 /

Protein length499 aa
Source databaseUniProt
Identifiers A2AKD7_MOUSE, A2AKD7, ENSMUSP00000105350.1, ENSMUSP00000105350
Source gene ENSMUSG00000027488
Alternative splicing A2AKD7_MOUSE, SNTA1_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

A2AKD7_MOUSE is shown as Snta1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Snta1

Protein A2AKD7_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04217Necroptosis

KEGG orthologous groups

KONameDescription
K24064SNTBbeta-syntrophin

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000105350 in eggNOG.

OGTaxonomic classDescription
LKOG3551All organisms (root)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
KOG3551Eukaryota (superkingdom)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
HT8IBMetazoa (kingdom)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
94FB1Chordata (phylum)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
5QWQASarcopterygii (superclass)alpha-syntrophin
8Z3D8Mammalia (class)alpha-syntrophin
4R93EEuarchontoglires (superorder)alpha-syntrophin
AI487Rodentia (order)alpha-syntrophin
8D5PFMyomorpha (suborder)alpha-syntrophin
H4BI7Bilateria (clade)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
7K9HFOpisthokonta (clade)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
9FMRRVertebrata (clade)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
CQH6JMuridae (family)alpha-syntrophin
AE0J6Murinae (subfamily)alpha-syntrophin
5PNBEMus (genus)alpha-syntrophin
HE1FCMus (subgenus)alpha-syntrophin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: