Domains within Danio rerio protein A8E7H6_DANRE (A8E7H6)

Zinc finger protein 532

Alternative representations: 1 /

Protein length1294 aa
Source databaseUniProt
Identifiers A8E7H6_DANRE, A8E7H6, ENSDARP00000120865.1, ENSDARP00000120865, E9QI93_DANRE, E9QI93, E9QC49_DANRE, E9QC49
Source gene ENSDARG00000052894
Alternative splicing ENSDARP00000114124.1, E9QBS5_DANRE, ENSDARP00000078470.4, A8E7H6_DANRE, ENSDARP00000118641.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

A8E7H6_DANRE is shown as znf532 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for znf532

Protein A8E7H6_DANRE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05168Herpes simplex virus 1 infection

KEGG orthologous groups

KONameDescription
K09228KRABKRAB domain-containing zinc finger protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7955.ENSDARP00000120865 in eggNOG.

OGTaxonomic classDescription
LKOG1721All organisms (root)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
9J00POtomorpha (cohort)zf-C2H2_11,zf-C2H2,zf-C2H2_6
KOG1721Eukaryota (superkingdom)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
HTXW4Metazoa (kingdom)transmembrane reductase [EC:7.2.1.3],zinc finger protein 687,zinc finger protein 592
93XH8Chordata (phylum)zinc finger protein 687,zinc finger protein 592
FXZAQActinopterygii (superclass)zf-C2H2,zf-C2H2_11,zf-C2H2_4
8NE9TNeopterygii (subclass)zf-C2H2,zf-C2H2_11,zf-C2H2_4
H554MBilateria (clade)transmembrane reductase [EC:7.2.1.3],zinc finger protein 687,zinc finger protein 592
7MTDYOpisthokonta (clade)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
9G260Vertebrata (clade)zinc finger protein 687,zinc finger protein 592
BES9DCyprinidae (family)zf-C2H2_11,zf-C2H2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: