Domains within Homo sapiens protein A8MWR2_HUMAN (A8MWR2)

WAS/WASL-interacting protein family member 2

Alternative representations: 1 /

Protein length182 aa
Source databaseUniProt
Identifiers A8MWR2_HUMAN, A8MWR2, ENSP00000377663.3, ENSP00000377663, H2RDY9_PANTR, H2RDY9, F6STZ6_MACMU, F6STZ6, A0A2I2ZL23_GORGO, A0A2I2ZL23, A0A2K5TR99_MACFA, A0A2K5TR99, A0A2K6QR22_RHIRO, A0A2K6QR22, A0A2I3M156_PAPAN, A0A2I3M156, A0A2K5IBN1_COLAP, A0A2K5IBN1, A0A2K5Z3W3_MANLE, A0A2K5Z3W3, G1QM73_NOMLE, G1QM73
Source gene ENSG00000171475
Alternative splicing J3KSA3_HUMAN, WIPF2_HUMAN, J3QQS0_HUMAN, A8MWR2_HUMAN, ENSP00000463149.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

A8MWR2_HUMAN is shown as WIPF2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for WIPF2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 61853.ENSNLEP00000002039 in eggNOG.

OGTaxonomic classDescription
LKOG4462All organisms (root)WAS/WASL-interacting protein,protein piccolo,DNA binding protein (fs(1)K10, female sterile(1)K10)
KOG4462Eukaryota (superkingdom)WAS/WASL-interacting protein,protein piccolo,DNA binding protein (fs(1)K10, female sterile(1)K10)
HW62YMetazoa (kingdom)WAS/WASL-interacting protein
943R5Chordata (phylum)WAS/WASL-interacting protein
5QFT9Sarcopterygii (superclass)WAS/WASL-interacting protein
8Z8YCMammalia (class)WAS/WASL-interacting protein
4RJACEuarchontoglires (superorder)WAS/WASL-interacting protein
4ZWWSPrimates (order)WAS/WASL-interacting protein
98M5PHaplorrhini (suborder)WAS/WASL-interacting protein
BVAFGSimiiformes (infraorder)WAS/WASL-interacting protein
9EG0ICatarrhini (parvorder)WAS/WASL-interacting protein
7MXYVOpisthokonta (clade)WAS/WASL-interacting protein
H3HBEBilateria (clade)WAS/WASL-interacting protein
9GD85Vertebrata (clade)WAS/WASL-interacting protein
FWY0QHominoidea (superfamily)WAS/WASL-interacting protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: