Domains within Mus musculus protein AGRP_MOUSE (P56473)

Agouti-related protein

Alternative representations: 1 /

Protein length131 aa
Source databaseUniProt
Identifiers AGRP_MOUSE, P56473, ENSMUSP00000005849.5, ENSMUSP00000005849, ENSMUSP00000142044.1, ENSMUSP00000142044, O35967, Q3UU47_MOUSE, Q3UU47, Q5J6B1_MOUSE, Q5J6B1, A0A0A6YX09_MOUSE, A0A0A6YX09
Source gene ENSMUSG00000005705
Alternative splicing AGRP_MOUSE, ENSMUSP00000141783.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

AGRP_MOUSE is shown as Agrp in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Agrp

Protein AGRP_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04920Adipocytokine signaling pathway

KEGG orthologous groups

KONameDescription
K05231AGRPagouti related protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000142044 in eggNOG.

OGTaxonomic classDescription
6WI1ZAll organisms (root)agouti related protein
5GK8REukaryota (superkingdom)agouti related protein
HTCWGMetazoa (kingdom)agouti related protein
94RINChordata (phylum)agouti related protein
5R9ZZSarcopterygii (superclass)agouti related protein
8ZN7ZMammalia (class)agouti related protein
4RHI8Euarchontoglires (superorder)agouti related protein
AI6CIRodentia (order)agouti related protein
8DFP6Myomorpha (suborder)agouti related protein
9G51FVertebrata (clade)agouti related protein
7I0KQOpisthokonta (clade)agouti related protein
H4UZWBilateria (clade)agouti related protein
CQFUVMuridae (family)agouti related protein
ADXRTMurinae (subfamily)agouti related protein
5PMGFMus (genus)agouti related protein
HE07HMus (subgenus)agouti related protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: