Domains within Homo sapiens protein ANR55_HUMAN (Q3KP44)

Ankyrin repeat domain-containing protein 55

Alternative representations: 1 /

Protein length614 aa
Source databaseUniProt
Identifiers ANR55_HUMAN, Q3KP44, ENSP00000342295.4, ENSP00000342295, B3KVT8, Q3KP45, Q9HAD3, Q3KP44-2
Source gene ENSG00000164512
Alternative splicing ANR55_HUMAN, D6RBD3_HUMAN, ENSP00000429421.1, D6R9N4_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ANR55_HUMAN is shown as ANKRD55 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ANKRD55

Protein ANR55_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05166Human T-cell leukemia virus 1 infection

KEGG orthologous groups

KONameDescription
K10999CESAcellulose synthase A [EC:2.4.1.12]
K06867K06867uncharacterized protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
Phosphorylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ANKRD55.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000342295 in eggNOG.

OGTaxonomic classDescription
LCOG0666All organisms (root)uncharacterized protein,Mce-associated membrane protein,cellulose synthase A [EC:2.4.1.12]
KOG0504Eukaryota (superkingdom)cellulose synthase A [EC:2.4.1.12],beta-mannan synthase [EC:2.4.1.32],uncharacterized protein
HUQR1Metazoa (kingdom)Ank_2,Ank_4,Ank
93KCIChordata (phylum)Ank_2,Ank_4,Ank
5R4G2Sarcopterygii (superclass)Ank_2,Ank,Ank_4
8Z59GMammalia (class)Ank_2,Ank_4,Ank
4RCGNEuarchontoglires (superorder)Ank_2,Ank,Ank_5
504AQPrimates (order)Ank_2
98QKQHaplorrhini (suborder)Ank_2
BVCCWSimiiformes (infraorder)Ank_2
9F1U8Catarrhini (parvorder)Ank_2
9FH77Vertebrata (clade)Ank_2,Ank_4,Ank
7J0C0Opisthokonta (clade)Ank_2,Ank_4,Ank
H4BMQBilateria (clade)Ank_2,Ank_4,Ank
FX400Hominoidea (superfamily)Ank_2
5NCQYHominidae (family)Ank_2
5Y0BSHomininae (subfamily)Ank_2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: