Domains within Drosophila melanogaster protein ARM_DROME (P18824)

Armadillo segment polarity protein

Alternative representations: 1 /

Protein length843 aa
Source databaseUniProt
Identifiers ARM_DROME, P18824, FBPP0089034, FBPP0304835, FBPP0089031, FBPP0089032, FBPP0089035, A4V3V0, O02371, Q0KHX2, Q8IRW7, Q9W546, B3P8S9_DROER, B3P8S9, M9PGG4_DROME, M9PGG4
Source gene FBgn0000117
Alternative splicing ARM_DROME, P18824-2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

ARM_DROME is shown as arm in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for arm

Protein ARM_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05226Gastric cancer
map05225Hepatocellular carcinoma

KEGG orthologous groups

KONameDescription
K00876udk, UCKuridine kinase [EC:2.7.1.48] iPath3
K02105CTNNB1catenin beta 1
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 54 PTMs annotated in this protein:

PTMCount
Phosphorylation32
Ubiquitination14
Acetylation4
Nitrosylation2
Oxidation1
Caspase cleavage aspartic acid1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein arm.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0089032 in eggNOG.

OGTaxonomic classDescription
EIVY8Endopterygota (cohort)catenin beta 1
LCOG0572All organisms (root)uridine kinase [EC:2.7.1.48],nicotinamide/nicotinate riboside kinase [EC:2.7.1.22 2.7.1.173],uracil phosphoribosyltransferase [EC:2.4.2.9]
FE4K0melanogaster subgroup (species subgroup)catenin beta 1
FV5GGmelanogaster group (species group)catenin beta 1
KOG4203Eukaryota (superkingdom)uridine kinase [EC:2.7.1.48],uracil phosphoribosyltransferase [EC:2.4.2.9],catenin beta 1
HW9Y2Metazoa (kingdom)catenin beta 1,junction plakoglobin
HIFR9Arthropoda (phylum)catenin beta 1
8656GHexapoda (subphylum)catenin beta 1
AH1D0Neoptera (infraclass)catenin beta 1
ANJZPDiptera (order)catenin beta 1
7NIWZOpisthokonta (clade)catenin beta 1,junction plakoglobin
H5F49Bilateria (clade)catenin beta 1,junction plakoglobin
EGTIFDrosophila (genus)catenin beta 1
50G7WSophophora (subgenus)catenin beta 1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: