Domains within Danio rerio protein B0V217_DANRE (B0V217)

Abl-interactor 2a

Alternative representations: 1 /

Protein length394 aa
Source databaseUniProt
Identifiers B0V217_DANRE, B0V217, ENSDARP00000075483.5, ENSDARP00000075483
Source gene ENSDARG00000058207
Alternative splicing B0V217_DANRE, B0V218_DANRE, B0V219_DANRE, UPI0003835D4B, ENSDARP00000136806.2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

B0V217_DANRE is shown as abi2a in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for abi2a

Protein B0V217_DANRE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05100Bacterial invasion of epithelial cells
map04810Regulation of actin cytoskeleton

KEGG orthologous groups

KONameDescription
K05751ABI2abl interactor 2
K13736ARHGAP10Rho GTPase-activating protein 10

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7955.ENSDARP00000075483 in eggNOG.

OGTaxonomic classDescription
LKOG2546All organisms (root)Rho GTPase-activating protein 10,abl interactor 2,abi gene family member 3
KOG2546Eukaryota (superkingdom)Rho GTPase-activating protein 10,abl interactor 2,abi gene family member 3
HV8U4Metazoa (kingdom)abl interactor 2,MAGUK p55 subfamily member 4
946BHChordata (phylum)abl interactor 2,MAGUK p55 subfamily member 4
FXFV2Actinopterygii (superclass)abl interactor 2,MAGUK p55 subfamily member 4
8MWTSNeopterygii (subclass)abl interactor 2,MAGUK p55 subfamily member 4
7JC46Opisthokonta (clade)abl interactor 2,MAGUK p55 subfamily member 4
H4CIWBilateria (clade)abl interactor 2,MAGUK p55 subfamily member 4
9FRUDVertebrata (clade)abl interactor 2,MAGUK p55 subfamily member 4

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: