Domains within Homo sapiens protein B1AP13_HUMAN (B1AP13)

Complement decay-accelerating factor

Alternative representations: 1 /

Protein length444 aa
Source databaseUniProt
Identifiers B1AP13_HUMAN, B1AP13, ENSP00000356030.2, ENSP00000356030, Q76N74, Q76N74_HUMAN, O18722_PANTR, O18722, Q76N73_PONPY, Q76N73
Source gene ENSG00000196352
Alternative splicing DAF_HUMAN, B1AP13_HUMAN, B1AP15_HUMAN, P08174-5, P08174-2, P08174-3, H3BLV0_HUMAN, ENSP00000495477.1, ENSP00000495069.1, ENSP00000493859.1, H7BY55_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

B1AP13_HUMAN is shown as CD55 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CD55

Protein B1AP13_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05416Viral myocarditis
map04145Phagosome
map04640Hematopoietic cell lineage

KEGG orthologous groups

KONameDescription
K06560MRC, CD206, CD280mannose receptor, C type
K04006DAF, CD55decay accelerating factor

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000356030 in eggNOG.

OGTaxonomic classDescription
LKOG4297All organisms (root)mannose receptor, C type,CUB and sushi domain-containing protein,E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
KOG4297Eukaryota (superkingdom)mannose receptor, C type,CUB and sushi domain-containing protein,E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
HU7A3Metazoa (kingdom)decay accelerating factor,complement component (3b/4b) receptor 1
93K8WChordata (phylum)decay accelerating factor,complement component (3b/4b) receptor 1
5RANWSarcopterygii (superclass)decay accelerating factor,complement component (3b/4b) receptor 1
8ZC0NMammalia (class)decay accelerating factor
4RFVZEuarchontoglires (superorder)decay accelerating factor
4ZT2ZPrimates (order)decay accelerating factor
98GY3Haplorrhini (suborder)decay accelerating factor
BV2FZSimiiformes (infraorder)decay accelerating factor
9ERKCCatarrhini (parvorder)decay accelerating factor
H4GWPBilateria (clade)decay accelerating factor,complement component (3b/4b) receptor 1
7GIHVOpisthokonta (clade)decay accelerating factor,complement component (3b/4b) receptor 1
9GUJPVertebrata (clade)decay accelerating factor,complement component (3b/4b) receptor 1
FX680Hominoidea (superfamily)decay accelerating factor
5N2NWHominidae (family)decay accelerating factor
5Y52THomininae (subfamily)decay accelerating factor

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: