Domains within Mus musculus protein B2C3G8_MOUSE (B2C3G8)

Signal transducer and activator of transcription

Alternative representations: 1 /

Protein length797 aa
Source databaseUniProt
Identifiers B2C3G8_MOUSE, B2C3G8, ENSMUSP00000102980.2, ENSMUSP00000102980, A2A5D3_MOUSE, A2A5D3, Q71UV3_MOUSE, Q71UV3
Source gene ENSMUSG00000004043
Alternative splicing STA5A_MOUSE, A2A5D4_MOUSE, ENSMUSP00000120039.1, B2C3G8_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

B2C3G8_MOUSE is shown as Stat5a in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Stat5a

Protein B2C3G8_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04630JAK-STAT signaling pathway
map04658Th1 and Th2 cell differentiation
map05203Viral carcinogenesis

KEGG orthologous groups

KONameDescription
K11224STAT5Bsignal transducer and activator of transcription 5B
K11225STAT6signal transducer and activator of transcription 6
K11223STAT5Asignal transducer and activator of transcription 5A

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000102980 in eggNOG.

OGTaxonomic classDescription
LKOG3667All organisms (root)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 1,signal transducer and activator of transcription 3
KOG3667Eukaryota (superkingdom)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 1,signal transducer and activator of transcription 3
HU8P6Metazoa (kingdom)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 3,signal transducer and activator of transcription 1
94PBXChordata (phylum)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 5A,signal transducer and activator of transcription 6
5QZR6Sarcopterygii (superclass)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 5A,signal transducer and activator of transcription 6
8ZJPWMammalia (class)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 5A
4R2YVEuarchontoglires (superorder)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 5A
AI5ICRodentia (order)signal transducer and activator of transcription 5A
8D58GMyomorpha (suborder)signal transducer and activator of transcription 5A
H4SJ1Bilateria (clade)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 3,signal transducer and activator of transcription 1
7MSZPOpisthokonta (clade)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 3,signal transducer and activator of transcription 1
9FBGXVertebrata (clade)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 5A,signal transducer and activator of transcription 6
CQ3T9Muridae (family)signal transducer and activator of transcription 5A
AE9VIMurinae (subfamily)signal transducer and activator of transcription 5A
5PNXYMus (genus)signal transducer and activator of transcription 5A
HEBI8Mus (subgenus)signal transducer and activator of transcription 5A

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: