Domains within Drosophila melanogaster protein B7YZV6_DROME (B7YZV6)

Scm-related gene containing four mbt domains, isoform C

Alternative representations: 1 /

Protein length1243 aa
Source databaseUniProt
Identifiers B7YZV6_DROME, B7YZV6, FBPP0288419
Source gene FBgn0032475
Alternative splicing FBpp0080069, SMBT_DROME, B7YZV6_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

B7YZV6_DROME is shown as Sfmbt in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Sfmbt

Protein B7YZV6_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03040Spliceosome

KEGG orthologous groups

KONameDescription
K24387L3MBTLlethal(3)malignant brain tumor-like protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 11 PTMs annotated in this protein:

PTMCount
Phosphorylation9
Proteolytic cleavage1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Sfmbt.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0288419 in eggNOG.

OGTaxonomic classDescription
EJ5AAEndopterygota (cohort)MBT,SAM_1,Ig_3
LKOG3766All organisms (root)lethal(3)malignant brain tumor-like protein,polycomb protein SCMH1,sex comb on midleg-like protein 2
FE41Zmelanogaster subgroup (species subgroup)MBT,SAM_1
FUZG8melanogaster group (species group)MBT,SAM_1
KOG3766Eukaryota (superkingdom)lethal(3)malignant brain tumor-like protein,polycomb protein SCMH1,sex comb on midleg-like protein 2
HSWM8Metazoa (kingdom)lethal(3)malignant brain tumor-like protein
HINTIArthropoda (phylum)MBT,SAM_1,Ig_3
85M1CHexapoda (subphylum)MBT,SAM_1,Ig_3
AGNTPNeoptera (infraclass)MBT,SAM_1,Ig_3
ANPNNDiptera (order)MBT,SAM_1,PrmA
H69BXBilateria (clade)lethal(3)malignant brain tumor-like protein
7P3HGOpisthokonta (clade)lethal(3)malignant brain tumor-like protein
EGUIJDrosophila (genus)MBT,SAM_1
50NBVSophophora (subgenus)MBT,SAM_1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: