Domains within Mus musculus protein CCNB1_MOUSE (P24860)

G2/mitotic-specific cyclin-B1

Alternative representations: 1 /

Protein length430 aa
Source databaseUniProt
Identifiers CCNB1_MOUSE, P24860, ENSMUSP00000071989.8, ENSMUSP00000071989, Q3TQW9_MOUSE, Q3TQW9
Source gene ENSMUSG00000041431
Alternative splicing CCNB1_MOUSE, Q68EM3_MOUSE, G3UY65_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

CCNB1_MOUSE is shown as Ccnb1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ccnb1

Protein CCNB1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04068FoxO signaling pathway
map05170Human immunodeficiency virus 1 infection

KEGG orthologous groups

KONameDescription
K05868CCNB1G2/mitotic-specific cyclin-B1
K21770CCNB2G2/mitotic-specific cyclin-B2
K21777CCNBG2/mitotic-specific cyclin-B, other

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 23 PTMs annotated in this protein:

PTMCount
Phosphorylation12
Ubiquitination8
Acetylation3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Ccnb1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000071989 in eggNOG.

OGTaxonomic classDescription
LKOG0653All organisms (root)G2/mitotic-specific cyclin-B, other,G2/mitotic-specific cyclin-B2,cyclin G2
KOG0653Eukaryota (superkingdom)G2/mitotic-specific cyclin-B, other,G2/mitotic-specific cyclin-B2,cyclin G2
HTZSGMetazoa (kingdom)G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin-B3,WD repeat-containing protein 41
93N9BChordata (phylum)G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin-B1,G2/mitotic-specific cyclin 2
5QI6VSarcopterygii (superclass)G2/mitotic-specific cyclin-B1,G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin 2
8Z0XPMammalia (class)G2/mitotic-specific cyclin-B1,G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin 2
4R6X9Euarchontoglires (superorder)G2/mitotic-specific cyclin-B1,G2/mitotic-specific cyclin 2,G2/mitotic-specific cyclin-B2
AIEBURodentia (order)G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin-B1
8DA1GMyomorpha (suborder)G2/mitotic-specific cyclin-B1
7ICZNOpisthokonta (clade)G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin-B3,G2/mitotic-specific cyclin 2
H67HWBilateria (clade)G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin-B3,G2/mitotic-specific cyclin-B1
9GN1MVertebrata (clade)G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin-B1,G2/mitotic-specific cyclin 2
CQE6HMuridae (family)G2/mitotic-specific cyclin-B1
AE1RNMurinae (subfamily)G2/mitotic-specific cyclin-B1
5PGVAMus (genus)G2/mitotic-specific cyclin-B1
HE889Mus (subgenus)G2/mitotic-specific cyclin-B1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: