Domains within Mus musculus protein CD3G_MOUSE (P11942)

T-cell surface glycoprotein CD3 gamma chain

Alternative representations: 1 /

Protein length182 aa
Source databaseUniProt
Identifiers CD3G_MOUSE, P11942, ENSMUSP00000002101.5, ENSMUSP00000002101, Q3U4Y3_MOUSE, Q3U4Y3
Source gene ENSMUSG00000002033
Alternative splicing CD3G_MOUSE, E0CXP3_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Amniota

Predicted functional partners

CD3G_MOUSE is shown as Cd3g in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Cd3g

Protein CD3G_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04658Th1 and Th2 cell differentiation

KEGG orthologous groups

KONameDescription
K06452CD3GT-cell surface glycoprotein CD3 gamma chain

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation3
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Cd3g.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000002101 in eggNOG.

OGTaxonomic classDescription
73X2QAll organisms (root)T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 delta chain
5G9Q7Eukaryota (superkingdom)T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 delta chain
HTNHFMetazoa (kingdom)T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 delta chain
93KHBChordata (phylum)T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 delta chain
5RCF3Sarcopterygii (superclass)T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 delta chain
8ZIS4Mammalia (class)T-cell surface glycoprotein CD3 gamma chain
4R5K1Euarchontoglires (superorder)T-cell surface glycoprotein CD3 gamma chain
AI8U3Rodentia (order)T-cell surface glycoprotein CD3 gamma chain
8DKRDMyomorpha (suborder)T-cell surface glycoprotein CD3 gamma chain
7H8GFOpisthokonta (clade)T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 delta chain
9FP89Vertebrata (clade)T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 delta chain
H5AHGBilateria (clade)T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 delta chain
CQ3BVMuridae (family)T-cell surface glycoprotein CD3 gamma chain
AE1HZMurinae (subfamily)T-cell surface glycoprotein CD3 gamma chain
5PXHSMus (genus)T-cell surface glycoprotein CD3 gamma chain
HECEGMus (subgenus)T-cell surface glycoprotein CD3 gamma chain

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: