Domains within Drosophila melanogaster protein CDGAP_DROME (Q9VIS1)

GTPase-activating protein CdGAPr

Alternative representations: 1 /

Protein length1843 aa
Source databaseUniProt
Identifiers CDGAP_DROME, Q9VIS1, FBPP0304488, FBPP0080851, Q6AWI4, Q8MSV9, Q9NCL1, M9PDR8_DROME, M9PDR8
Source gene FBgn0032821
Alternative splicing E1JHM0_DROME, E1JHM1_DROME, CDGAP_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

CDGAP_DROME is shown as CdGAPr in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CdGAPr

Protein CDGAP_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04150mTOR signaling pathway

KEGG orthologous groups

KONameDescription
K20647ARHGAP32Rho GTPase-activating protein 32

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 43 PTMs annotated in this protein:

PTMCount
Phosphorylation43

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein CdGAPr.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0304488 in eggNOG.

OGTaxonomic classDescription
LKOG1449All organisms (root)Rho GTPase-activating protein 32,Rho GTPase-activating protein 31,proline-rich protein 5
FV575melanogaster group (species group)Rho GTPase-activating protein 32
FDWISmelanogaster subgroup (species subgroup)Rho GTPase-activating protein 32
EJ339Endopterygota (cohort)Rho GTPase-activating protein 32
KOG1449Eukaryota (superkingdom)Rho GTPase-activating protein 32,Rho GTPase-activating protein 31,proline-rich protein 5
HTHXQMetazoa (kingdom)Rho GTPase-activating protein 32,Rho GTPase-activating protein 31,Rho GTPase-activating protein 30
HHU5DArthropoda (phylum)Rho GTPase-activating protein 32
85CWJHexapoda (subphylum)Rho GTPase-activating protein 32
AHP70Neoptera (infraclass)Rho GTPase-activating protein 32
ANIPKDiptera (order)Rho GTPase-activating protein 32
H3U3YBilateria (clade)Rho GTPase-activating protein 32,Rho GTPase-activating protein 31,Rho GTPase-activating protein 30
7MDBPOpisthokonta (clade)Rho GTPase-activating protein 32,Rho GTPase-activating protein 31,Rho GTPase-activating protein 30
EH3D3Drosophila (genus)Rho GTPase-activating protein 32
50AT8Sophophora (subgenus)Rho GTPase-activating protein 32

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: