Domains within Homo sapiens protein CLM7_HUMAN (A8K4G0)

CMRF35-like molecule 7

Alternative representations: 1 /

Protein length201 aa
Source databaseUniProt
Identifiers CLM7_HUMAN, A8K4G0, ENSP00000376397.2, ENSP00000376397, Q1EG73, Q8IX40, Q8N6D1
Source gene ENSG00000178789
Alternative splicing CLM7_HUMAN, J9JID3_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

CLM7_HUMAN is shown as CD300LB in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CD300LB

Protein CLM7_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04672Intestinal immune network for IgA production
map04810Regulation of actin cytoskeleton

KEGG orthologous groups

KONameDescription
K20395CD300B_D_FCO300B/D/F antigen

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000376397 in eggNOG.

OGTaxonomic classDescription
LKOG3637All organisms (root)CO300B/D/F antigen,polymeric immunoglobulin receptor,integrin alpha 6
KOG3637Eukaryota (superkingdom)CO300B/D/F antigen,polymeric immunoglobulin receptor,integrin alpha 6
HTVQAMetazoa (kingdom)CO300B/D/F antigen,polymeric immunoglobulin receptor,CD300 antigen
93R4WChordata (phylum)CO300B/D/F antigen,polymeric immunoglobulin receptor,CD300 antigen
5R63FSarcopterygii (superclass)CO300B/D/F antigen
8YVG6Mammalia (class)CO300B/D/F antigen
4R5ZGEuarchontoglires (superorder)CO300B/D/F antigen
4ZUAZPrimates (order)CO300B/D/F antigen
98BI8Haplorrhini (suborder)CO300B/D/F antigen
BVDWWSimiiformes (infraorder)CO300B/D/F antigen
9EVXDCatarrhini (parvorder)CO300B/D/F antigen
9G844Vertebrata (clade)CO300B/D/F antigen,polymeric immunoglobulin receptor,CD300 antigen
H53I1Bilateria (clade)CO300B/D/F antigen,polymeric immunoglobulin receptor,CD300 antigen
7NG1TOpisthokonta (clade)CO300B/D/F antigen,polymeric immunoglobulin receptor,CD300 antigen
FXA5EHominoidea (superfamily)CO300B/D/F antigen
5NBUIHominidae (family)CO300B/D/F antigen
5Y8JEHomininae (subfamily)CO300B/D/F antigen

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: