Domains within Mus musculus protein COFA1_MOUSE (O35206)

Collagen alpha-1(XV) chain

Alternative representations: 1 /

Protein length1367 aa
Source databaseUniProt
Identifiers COFA1_MOUSE, O35206, ENSMUSP00000099981.4, ENSMUSP00000099981, A2AJY3, Q3UZ71, Q9EQD9, A2AJY6_MOUSE, A2AJY6
Source gene ENSMUSG00000028339
Alternative splicing A2AJY2_MOUSE, COFA1_MOUSE, A2AJY4_MOUSE, A2AJY5_MOUSE, ENSMUSP00000118637.1, A2AJY7_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

COFA1_MOUSE is shown as Col15a1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Col15a1

Protein COFA1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04974Protein digestion and absorption

KEGG orthologous groups

KONameDescription
K06823COL18Acollagen type XVIII alpha
K08135COL15Acollagen type XV alpha

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 6 PTMs annotated in this protein:

PTMCount
Phosphorylation4
O-GalNAc glycosylation1
O-linked glycosylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Col15a1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000099981 in eggNOG.

OGTaxonomic classDescription
LKOG3546All organisms (root)collagen type XVIII alpha,collagen type XV alpha,collagen type III alpha
KOG3546Eukaryota (superkingdom)collagen type XVIII alpha,collagen type XV alpha,collagen type III alpha
HT19NMetazoa (kingdom)collagen type XVIII alpha,collagen type XV alpha,collagen type III alpha
94HR4Chordata (phylum)collagen type XVIII alpha,collagen type XV alpha
5RDPNSarcopterygii (superclass)collagen type XVIII alpha,collagen type XV alpha
8YV31Mammalia (class)collagen type XVIII alpha,collagen type XV alpha
4RFYUEuarchontoglires (superorder)collagen type XV alpha
AI097Rodentia (order)collagen type XV alpha
8D6PDMyomorpha (suborder)collagen type XV alpha
7KQDMOpisthokonta (clade)collagen type XVIII alpha,collagen type XV alpha,collagen type III alpha
H5C4MBilateria (clade)collagen type XVIII alpha,collagen type XV alpha
9G11GVertebrata (clade)collagen type XVIII alpha,collagen type XV alpha
CQBQQMuridae (family)collagen type XV alpha
AE67VMurinae (subfamily)collagen type XV alpha
5PXJGMus (genus)collagen type XV alpha
HE1CAMus (subgenus)collagen type XV alpha

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: