Domains within Drosophila melanogaster protein CPR1_DROME (Q9VN93)

Putative cysteine proteinase CG12163

Alternative representations: 1 /

Protein length614 aa
Source databaseUniProt
Identifiers CPR1_DROME, Q9VN93, FBPP0078465, Q867H7, Q9VN92
Source gene FBgn0260462
Alternative splicing D3PK81_DROME, CPR1_DROME, H5V8F3_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

CPR1_DROME is shown as CG12163 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CG12163

Protein CPR1_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04142Lysosome
map04210Apoptosis
map04626Plant-pathogen interaction

KEGG orthologous groups

KONameDescription
K01373CTSFcathepsin F [EC:3.4.22.41]
K01365CTSLcathepsin L [EC:3.4.22.15]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
N-linked glycosylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein CG12163.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0078465 in eggNOG.

OGTaxonomic classDescription
FE038melanogaster subgroup (species subgroup)cathepsin F [EC:3.4.22.41]
LCOG4870All organisms (root)cathepsin L [EC:3.4.22.15],cathepsin B [EC:3.4.22.1],cathepsin F [EC:3.4.22.41]
FUYD6melanogaster group (species group)cathepsin F [EC:3.4.22.41]
EJGSVEndopterygota (cohort)cathepsin F [EC:3.4.22.41]
KOG1542Eukaryota (superkingdom)cathepsin F [EC:3.4.22.41],cathepsin O [EC:3.4.22.42],cathepsin W [EC:3.4.22.-]
HTMSTMetazoa (kingdom)cathepsin F [EC:3.4.22.41]
HI061Arthropoda (phylum)cathepsin F [EC:3.4.22.41]
85ZRQHexapoda (subphylum)cathepsin F [EC:3.4.22.41]
AH52JNeoptera (infraclass)cathepsin F [EC:3.4.22.41]
ANW4YDiptera (order)cathepsin F [EC:3.4.22.41]
7IY2KOpisthokonta (clade)cathepsin F [EC:3.4.22.41]
H4HVIBilateria (clade)cathepsin F [EC:3.4.22.41]
EH0RYDrosophila (genus)cathepsin F [EC:3.4.22.41]
50KJYSophophora (subgenus)cathepsin F [EC:3.4.22.41]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: