Domains within Mus musculus protein DDX3Y_MOUSE (Q62095)

ATP-dependent RNA helicase DDX3Y

Alternative representations: 1 /

Protein length658 aa
Source databaseUniProt
Identifiers DDX3Y_MOUSE, Q62095, ENSMUSP00000088729.5, ENSMUSP00000088729, Q9QWS9
Source gene ENSMUSG00000069045
Alternative splicing DDX3Y_MOUSE, A0A087WQV7_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

DDX3Y_MOUSE is shown as Ddx3y in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ddx3y

Protein DDX3Y_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03018RNA degradation
map05203Viral carcinogenesis

KEGG orthologous groups

KONameDescription
K11594DDX3X, belATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
K05592deaD, cshAATP-dependent RNA helicase DeaD [EC:5.6.2.7]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 34 PTMs annotated in this protein:

PTMCount
Phosphorylation25
Ubiquitination6
Acetylation2
Nitrosylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Ddx3x.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000088729 in eggNOG.

OGTaxonomic classDescription
LCOG0513All organisms (root)ATP-dependent RNA helicase DeaD [EC:3.6.4.13],ATP-dependent RNA helicase RhlE [EC:3.6.4.13],ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13]
KOG0335Eukaryota (superkingdom)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13],interleukin 31 receptor subunit alpha
HUEJ6Metazoa (kingdom)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13],interleukin 31 receptor subunit alpha
93S7ZChordata (phylum)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13],interleukin 31 receptor subunit alpha
5RCG9Sarcopterygii (superclass)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],interleukin 31 receptor subunit alpha,probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13]
8Z2IZMammalia (class)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13]
4RGHCEuarchontoglires (superorder)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13]
AIDWSRodentia (order)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13]
8DDK4Myomorpha (suborder)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13]
H5QGYBilateria (clade)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13],interleukin 31 receptor subunit alpha
9GC6QVertebrata (clade)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13],interleukin 31 receptor subunit alpha
7NYFPOpisthokonta (clade)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13],interleukin 31 receptor subunit alpha
CQB6FMuridae (family)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13]
AE3H1Murinae (subfamily)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13]
5PWGIMus (genus)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13]
HE2KPMus (subgenus)ATP-dependent RNA helicase DDX3X [EC:3.6.4.13],ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: