Domains within Drosophila melanogaster protein E1JHA6_DROME (E1JHA6)

Uninflatable, isoform C

Alternative representations: 1 /

Protein length3589 aa
Source databaseUniProt
Identifiers E1JHA6_DROME, E1JHA6, FBPP0297915, FBPP0297917, FBPP0291372, FBPP0297916
Source gene FBgn0031879
Alternative splicing E1JHA6_DROME, Q9VM55_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

E1JHA6_DROME is shown as uif in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for uif

Protein E1JHA6_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05165Human papillomavirus infection

KEGG orthologous groups

KONameDescription
K00430E1.11.1.7peroxidase [EC:1.11.1.7] iPath3
K04659THBS2Sthrombospondin 2/3/4/5
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0297917 in eggNOG.

OGTaxonomic classDescription
FUUQVmelanogaster group (species group)Ephrin_rec_like,Sushi,EGF
FE13Kmelanogaster subgroup (species subgroup)Sushi,Ephrin_rec_like,CUB
7553HAll organisms (root)peroxidase [EC:1.11.1.7],transmembrane channel-like protein,thrombospondin 2/3/4/5
EJ59AEndopterygota (cohort)EGF,Ephrin_rec_like,Sushi
KOG1217Eukaryota (superkingdom)peroxidase [EC:1.11.1.7],transmembrane channel-like protein,thrombospondin 2/3/4/5
HSY91Metazoa (kingdom)thrombospondin 2/3/4/5,delta,matrilin
HIM1FArthropoda (phylum)EGF,Ephrin_rec_like,Sushi
85UDNHexapoda (subphylum)EGF,Ephrin_rec_like,Sushi
AHN6JNeoptera (infraclass)EGF,Ephrin_rec_like,Sushi
ANDIXDiptera (order)EGF,Ephrin_rec_like,Sushi
H4QFHBilateria (clade)thrombospondin 2/3/4/5,delta,matrilin
7NXWDOpisthokonta (clade)thrombospondin 2/3/4/5,delta,matrilin
EH48WDrosophila (genus)EGF,Ephrin_rec_like,Sushi
50JBTSophophora (subgenus)Ephrin_rec_like,EGF,Sushi

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: